Protein Alignment CG14160 and ITR2

DIOPT Version :10

• Sequence 1: NP_648380.2
• Gene: CG14160 / 39177
• FlyBaseID: FBgn0036066
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 548
• Identity: 105/548 - (19%)
• Similarity: 181/548 - (33%)
• Gaps: 165/548 - (30%)

  Fly     2 PMLPTIEEEAKLSWIRLMWKYRLQFQSMASASIVFVGCGMRLAWSIFDTPAGKFLNNHNTHNLMM 66
            |.:.|:...|.:|  ..|:.|...:.|.|..||                       |.:..|.::
Yeast   107 PFIITLTFVASIS--GFMFGYDTGYISSALISI-----------------------NRDLDNKVL 146

  Fly    67 SW----FIGAA--VGALL--------AALFVQRVTKNVAYTSSGFLMIIAGILNVVLPQHFLAAC 117
            ::    .|.||  :|||:        |.:|.:|    .....|..:.:|..||.:...:.:..|.
Yeast   147 TYGEKELITAATSLGALITSVGAGTAADVFGRR----PCLMFSNLMFLIGAILQITAHKFWQMAA 207

  Fly   118 YSSVSVGAAYGLTQIQALVTGSEVAHKSIRGMLLSCEKIFLWLGVCMQVFYTRVWHNLRPLDTQG 182
             ..:.:|...|:..:.:.:..||:|.|.|||.|.....  |||.....:.|             |
Yeast   208 -GRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINS--LWLTGGQLIAY-------------G 256

  Fly   183 YEMHIDQLHG--MVLAGLGLGAVILALA-----------HRLESPLLLLHQERDMAVGETLKALH 234
            ....::.:..  .:|.||.|...:|..:           :.::..|.........:...|...:.
Yeast   257 CGAGLNHVKNGWRILVGLSLIPTVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEII 321

  Fly   235 GQSTTELVRLREDCRQLHSARDWERFVEEPEESVADWRVWARRILPFFKVLLLRCFATLAVSLSY 299
            .|...||..|.:.....:....:...|:|           ...:...|:.|::.|      .|..
Yeast   322 DQKVEELSSLNQSIPGKNPITKFWNMVKE-----------LHTVPSNFRALIIGC------GLQA 369

  Fly   300 NRAFVVVSWHGLECDMNCMYWLAFAGLIGSVLG----------------------AFVVDWQGRR 342
            .:.|  ..|:.|      ||   |:|.|...:|                      .|.:|..|||
Yeast   370 IQQF--TGWNSL------MY---FSGTIFETVGFKNSSAVSIIVSGTNFVFTLIAFFCIDKIGRR 423

  Fly   343 KVCSLSLFLAGVVIVMV-GGVFDHLESVKRSFYDINLLVIALLMLLFEVIVAGGVAVPALVYTAE 406
            .:  |.:.|.|:.:.:| ..:..|...:|.:..|             .|:.:.|.:...:|..
Yeast   424 YI--LLIGLPGMTVALVICAIAFHFLGIKFNGAD-------------AVVASDGFSSWGIVII-- 471

  Fly   407 AFSIAHKARCLAGI---------LIVEQLLQLGLLLATFEHY---ITVSVFFFTI-------GVF 452
            .|.|.:.|....||         |..:.:..:|...||..::   :.::..|.|:       |.|
Yeast   472 VFIIVYAAFYALGIGTVPWQQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTF 536

  Fly   453 SFIVGL----TVFMFM--PETRQLTLYE 474
            ||..|:    |:|.:.  ||...|.|.|
Yeast   537 SFFAGVACLSTIFCYFCYPELSGLELEE 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14160	NP_648380.2	None
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	98/530 (18%)