Protein Alignment CG14160 and SLC2A1

DIOPT Version :10

• Sequence 1: NP_648380.2
• Gene: CG14160 / 39177
• FlyBaseID: FBgn0036066
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 119/525 - (22%)
• Similarity: 201/525 - (38%)
• Gaps: 145/525 - (27%)

  Fly     7 IEEEAKLSWIR------------LMWKYRLQFQSMASASIVFVGCGMRLAWSIFDTPAGKFLNNH 59
            |||....:|:.            .:|.        .|.:|..|| ||..::|:     |.|:|..
Human    40 IEEFYNQTWVHRYGESILPTTLTTLWS--------LSVAIFSVG-GMIGSFSV-----GLFVNRF 90

  Fly    60 NTHN--LMMSWFIGAAVGALLAALFVQRVTKNVAYTSSGFLMIIAGILNVVLPQHFLAACYSSVS 122
            ...|  |||:         |||  ||..|....:.....|.|:|.|        .|:...|..::
Human    91 GRRNSMLMMN---------LLA--FVSAVLMGFSKLGKSFEMLILG--------RFIIGVYCGLT 136

  Fly   123 VGAAYGLTQIQALVTGSEVAHKSIRGMLLSCEKIFLWLGVCM-QVFYTRVWHNLRPLDTQGYEMH 186
            .|       ...:..| ||:..::||.|.:..::.:.:|:.: |||                  .
Human   137 TG-------FVPMYVG-EVSPTALRGALGTLHQLGIVVGILIAQVF------------------G 175

  Fly   187 IDQLHG------MVLAGLGLGAVI--LALAHRLESP-LLLLHQERDMAVGETLKALHGQS--TTE 240
            :|.:.|      ::|:.:.:.|::  :.|....||| .||:::..:......||.|.|.:  |.:
Human   176 LDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240

  Fly   241 LVRLREDCRQLHSARDWERFVEEPEESVADWRVWARRILPFFKVLLLRCFATLAVSLSYNRAFVV 305
            |..::|:.||:..           |:.|.        ||..|:....|....:||.|..::..
Human   241 LQEMKEESRQMMR-----------EKKVT--------ILELFRSPAYRQPILIAVVLQLSQQL-- 284

  Fly   306 VSWHGLECDMNCMYWLAF-----AGL-------IGS--------VLGAFVVDWQGRRKVCSLSLF 350
                   ..:|.:::.:.     ||:       |||        |:..|||:..|||.:..:.|.
Human   285 -------SGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLA 342

  Fly   351 -LAGVVIVMVGGVFDHLESVKRSFYDINLLVIALLMLLFEVIVAGGVAVPALVYTAEAFSIAHK- 413
             :||..|:|...: ..||.:....| ::::.|...:..|||   |...:|..: .||.||...:
Human   343 GMAGCAILMTIAL-ALLEQLPWMSY-LSIVAIFGFVAFFEV---GPGPIPWFI-VAELFSQGPRP 401

  Fly   414 -ARCLAGILIVEQLLQLGLLLATFEHYITVSVF-FFTIGVFSFIVGLTVFMFMPETRQLTLYECL 476
             |..:||.........:|:.....|......|| .||:.:..|.: .|.|. :|||:..|..|..
Human   402 AAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFI-FTYFK-VPETKGRTFDEIA 464

  Fly   477 LKFKK 481
            ..|::
Human   465 SGFRQ 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14160	NP_648380.2	None
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	116/512 (23%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		0/2 (0%)