Protein Alignment CG14160 and SLC2A9

DIOPT Version :10

• Sequence 1: NP_648380.2
• Gene: CG14160 / 39177
• FlyBaseID: FBgn0036066
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_011512158.1
• Gene: SLC2A9 / 56606
• HGNCID: 13446
• Length: 615
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 106/499 - (21%)
• Similarity: 180/499 - (36%)
• Gaps: 157/499 - (31%)

  Fly    20 WKYRLQFQSMASA---SIVFVGCGMRLAWSIFDTPAGKFLNNH----------NTHNLMMSWFIG 71
            |...|...|:|.|   |.::   |..|:.....||..|...|.          :...|.:.|.:.
Human    52 WSCSLLVASLAGAFGSSFLY---GYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVT 113

  Fly    72 A---AVGALLAALFVQRV-----TKNVAYTSSGFLMIIAGILNVVLPQHFLAACYSSVSVGAAYG 128
            .   |:|.|:..|.|:.:     .|:....::||.:..|          .|.||  |:..||
Human   114 VSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAA----------LLMAC--SLQAGA--- 163

  Fly   129 LTQIQALVTG-------------------SEVAHKSIRGMLLSCEKIFLWLGVCMQVFYTRVWHN 174
               .:.|:.|                   ||::.|.|||.|.....||    :|:.||..::
Human   164 ---FEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIF----ICIGVFTGQL--- 218

  Fly   175 LRPLDTQGYEMHIDQLHGMVLAGLGLGAVI--LALAHRLESP-LLLLHQERDMAVGETLKALHGQ 236
            |...:..|.|.....|.|:::    :.||:  |:|....:|| .|||.:..:....:..:...|:
Human   219 LGLPELLGKESTWPYLFGVIV----VPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGK 279

  Fly   237 STTELVRLREDCRQLHSARDWERFVEEPEESVADWRVWARRILPFFKVL-LLRCFATLAVSLSYN 300
            :...                     :|.||.:|:.||  :|.:....|| |||     |..:.:.
Human   280 ADVS---------------------QEVEEVLAESRV--QRSIRLVSVLELLR-----APYVRWQ 316

  Fly   301 RAFVVVSWHGLE-CDMNCMYW--------------------LAFAGL--IGSVLGAFVVDWQGRR 342
            ...|:|:....: |.:|.:::                    |:..|:  :.:|....|::..|||
Human   317 VVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRR 381

  Fly   343 KVC-----SLSLFLAGVVIVMVGGVFDHLESVKRSFYDINLLVIALLMLLFEVIVAGGVAVPALV 402
            .:.     .:.||...:.|.:.  :.||...|.      .|.::.:|.::.. ..:|...:| .:
Human   382 PLLIGGFGLMGLFFGTLTITLT--LQDHAPWVP------YLSIVGILAIIAS-FCSGPGGIP-FI 436

  Fly   403 YTAE---------AFSIAHKARCLA----GILIVEQLLQLGLLL 433
            .|.|         ||.||.....|:    |:|.  ..:||.|||
Human   437 LTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLF--PFIQLLLLL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14160	NP_648380.2	None
SLC2A9	XP_011512158.1	MFS_GLUT_Class2	59..466	CDD:340990	97/476 (20%)