Protein Alignment Dronc and Casp6

DIOPT Version :10

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_113963.2
• Gene: Casp6 / 83584
• RGDID: 70967
• Length: 277
• Species: Rattus norvegicus
• Alignment Length: 277
• Identity: 76/277 - (27%)
• Similarity: 131/277 - (47%)
• Gaps: 41/277 - (14%)

  Fly   187 YKMQSRFNRGVLLMVN------IMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQF 245
            |||..: .||..|:.|      .:..|:  ||...|::|  :|...|.||.|.:..:.::..::.
  Rat    20 YKMDHK-RRGTALIFNHERFFWHLALPE--RRGTNADRD--NLTRRFSELGFEVKCFNDLRAEEL 79

  Fly   246 FKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKP 310
            ...:..|::||:| :.:||:.|.::||   ||.....:  .:.:::|.:...|:..||..||.||
  Rat    80 LLKIHEVSTSSHV-DADCFLCVFLSHG---EGNHIYAY--DAKIEIQTLTGLFKGDKCQSLVGKP 138

  Fly   311 KVLMFPFCRGDEYDLGHPKNQGNLMEPVYTA-----QEEKWPDTQTEGIPSPSTNVPSLADTLVC 370
            |:.:...|||.::|:           ||...     |.:|..|..|:...:....:|:.||.|:|
  Rat   139 KIFIIQACRGSQHDV-----------PVVPLDVVDHQTDKLDDNVTQVDAASVYTLPAGADFLMC 192

  Fly   371 YANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRT-------KKGSMQ 428
            |:...||.:||:...||||||..|:::|.|....:..::|...:..|..:|.       ..|..|
  Rat   193 YSVAEGYYSHRETVNGSWYIQDLCEMLARHGSSLEFTELLTLVNRKVSQRRVDFCKDPGAIGKKQ 257

  Fly   429 TGAYDNLGFNKKLYFNP 445
            ...:.:: ..|||:|.|
  Rat   258 VPCFASM-LTKKLHFCP 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018
		CASc	186..443	CDD:237997	74/273 (27%)
Casp6	NP_113963.2	CASc	20..273	CDD:214521	75/275 (27%)
		Tri-arginine exosite. /evidence=ECO:0000250|UniProtKB:P55212	25..27		0/2 (0%)
		130's region. /evidence=ECO:0000250|UniProtKB:P55212	108..125		1/18 (6%)