Protein Alignment Dronc and Casp2

DIOPT Version :9

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_038964243.1
• Gene: Casp2 / 64314
• RGDID: 69274
• Length: 470
• Species: Rattus norvegicus
• Alignment Length: 484
• Identity: 115/484 - (23%)
• Similarity: 195/484 - (40%)
• Gaps: 92/484 - (19%)

  Fly     9 GMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHR 73
            ||...|:|.::||..:|.:......|....:::.|:|::| |......|..|:         |:.
  Rat    31 GMHPDHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEM-RELIQAKGGSFS---------QNV 85

  Fly    74 RLLLKITQRGPTAYNLLINALRNI--NCLDAAVLLESVD----------ESDSRPPFI---SLNE 123
            .||..:.:|||.|::....|||..  ..|:..:|....|          :.||..||.   |...
  Rat    86 ELLNLLPKRGPQAFDAFCEALRETRQGHLEDLLLTTLSDIQHILPPLSCDYDSSLPFSVCESCPP 150

  Fly   124 RRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYK 188
            .:.||.|.|.::.........||   |:.:|   .||              :.:.....:  .|:
  Rat   151 HKQSRLSTDTMEHSLDNGDGPPC---LQVKP---CTP--------------EFYQAHYQL--AYR 193

  Fly   189 MQSRFNRGVLLMVNIMDYPDQN--RRRIGAEKDSKSLIHLFQELNFTIFP-YGNVNQDQFFKLLT 250
            :||: .||:.|:::.:.:..:.  ..|.|.:.|..:|:.||:.|.:.:.. |....|...|:|.:
  Rat   194 LQSQ-PRGLALVMSNVHFTGEKDLEFRSGGDVDHTTLVTLFKLLGYNVHVLYDQTAQFHRFQLYS 257

  Fly   251 MV--------TSSSYVQN---------TECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHF 298
            .:        .....:||         |:..::.|::||  |||  .:...||.::.:|::...|
  Rat   258 GIYKKYPKGQEMQEKLQNFAQLPAHRVTDSCIVALLSHG--VEG--GIYGVDGKLLQLQEVFRLF 318

  Fly   299 QTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPS 363
            ..|.||.|.||||:.....|||||.|.|..:..|.     ..||.....::...........:|:
  Rat   319 DNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGK-----NHAQSPGCEESDAGKEELMKMRLPT 378

  Fly   364 LADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNK-------- 420
            .:|.:..||...|....|:...|||||:...||.::.|.|..:.|:|.|.:..:..:
  Rat   379 RSDMICGYACLKGNAAMRNTKRGSWYIEALTQVFSERACDMHVADMLVKVNALIKEREGYAPGTE 443

  Fly   421 --RTKKGSMQTGAYDNLGFNKKLYFNPGF 447
              |.|:.|.....     ..::||..||:
  Rat   444 FHRCKEMSEYCST-----LCQQLYLFPGY 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	21/89 (24%)
		CASc	186..443	CDD:237997	70/286 (24%)
Casp2	XP_038964243.1	CARD_CASP2	32..118	CDD:260040	24/95 (25%)
		CASc	192..465	CDD:214521	71/287 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346252
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1092723at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.710