Protein Alignment Dronc and Casp2

DIOPT Version :10

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_071967.2
• Gene: Casp2 / 64314
• RGDID: 69274
• Length: 452
• Species: Rattus norvegicus
• Alignment Length: 467
• Identity: 113/467 - (24%)
• Similarity: 191/467 - (40%)
• Gaps: 76/467 - (16%)

  Fly     9 GMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHR 73
            ||...|:|.::||..:|.:......|....:::.|:|::| |......|..|:         |:.
  Rat    31 GMHPDHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEM-RELIQAKGGSFS---------QNV 85

  Fly    74 RLLLKITQRGPTAYNLLINALRNI--NCLDAAVLLESVD----------ESDSRPPFI---SLNE 123
            .||..:.:|||.|::....|||..  ..|:..:|....|          :.||..||.   |...
  Rat    86 ELLNLLPKRGPQAFDAFCEALRETRQGHLEDLLLTTLSDIQHILPPLSCDYDSSLPFSVCESCPP 150

  Fly   124 RRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYK 188
            .:.||.|.|.::.........||   |:.:|   .||              :.:.....:  .|:
  Rat   151 HKQSRLSTDTMEHSLDNGDGPPC---LQVKP---CTP--------------EFYQAHYQL--AYR 193

  Fly   189 MQSRFNRGVLLMVNIMDYPDQN--RRRIGAEKDSKSLIHLFQELNFTIFP-YGNVNQDQFFKLLT 250
            :||: .||:.|:::.:.:..:.  ..|.|.:.|..:|:.||:.|.:.:.. |....|:...||..
  Rat   194 LQSQ-PRGLALVMSNVHFTGEKDLEFRSGGDVDHTTLVTLFKLLGYNVHVLYDQTAQEMQEKLQN 257

  Fly   251 MVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMF 315
            .....::.....| ::.|::||  |||  .:...||.::.:|::...|..|.||.|.||||:...
  Rat   258 FAQLPAHRVTDSC-IVALLSHG--VEG--GIYGVDGKLLQLQEVFRLFDNANCPSLQNKPKMFFI 317

  Fly   316 PFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTH 380
            ..|||||.|.|..:..|.     ..||.....::...........:|:.:|.:..||...|....
  Rat   318 QACRGDETDRGVDQQDGK-----NHAQSPGCEESDAGKEELMKMRLPTRSDMICGYACLKGNAAM 377

  Fly   381 RDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNK----------RTKKGSMQTGAYDNL 435
            |:...|||||:...||.::.|.|..:.|:|.|.:..:..:          |.|:.|.....
  Rat   378 RNTKRGSWYIEALTQVFSERACDMHVADMLVKVNALIKEREGYAPGTEFHRCKEMSEYCST---- 438

  Fly   436 GFNKKLYFNPGF 447
             ..::||..||:
  Rat   439 -LCQQLYLFPGY 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	21/89 (24%)
		CASc	186..443	CDD:237997	68/269 (25%)
Casp2	NP_071967.2	CASc	192..447	CDD:214521	69/270 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..349		4/26 (15%)
		CARD_CASP2	32..118	CDD:260040	24/95 (25%)