DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dronc and Casp7

DIOPT Version :9

Sequence 1:	NP_524017.1	Gene:	Dronc / 39173	FlyBaseID:	FBgn0026404	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_071596.1	Gene:	Casp7 / 64026	RGDID:	620944	Length:	303	Species:	Rattus norvegicus

Alignment Length:	276	Identity:	72/276 - (26%)
Similarity:	121/276 - (43%)	Gaps:	49/276 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 TYKMQSRFNR-GVLLMVNIMDYPDQNRR--RIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFK 247
            ||..:..|.: |..:::|..::......  |.|.:||:::|...|:.|.|.:..|.:.:..:...
  Rat    57 TYLYRMDFEKMGKCIIINNKNFDKATGMDVRNGTDKDAEALFKCFRSLGFEVTVYNDCSCAKMQD 121

  Fly   248 LLTMVTSSSYVQNTECFVMVLMTHG--NSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKP 310
            ||...:...: .|:.||..||::||  |.:.||      || |..::.:..||:..:|..|:.||
  Rat   122 LLRRASEEDH-SNSACFACVLLSHGEENLIYGK------DG-VTPIKDLTAHFRGDRCKTLLEKP 178

  Fly   311 KVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTP 375
            |:.....|||.|.|.|              .|.:..|...|:.  :|...:|..||.|..|:..|
  Rat   179 KLFFIQACRGTELDDG--------------IQADSGPINDTDA--NPRYKIPVEADFLFAYSTVP 227

  Fly   376 GYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFN-- 438
            ||.:.|:...|||::|..|.::.:|..|.::..||.:.::.|......:.       |:..||
  Rat   228 GYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVNDRVARHFESQS-------DDPRFNEK 285

  Fly   439 -----------KKLYF 443
                       |:|||
  Rat   286 KQIPCMVSMLTKELYF 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018
Dronc	NP_524017.1	CASc	186..443	CDD:237997	70/274 (26%)
Casp7	NP_071596.1	CASc	60..301	CDD:237997	68/271 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010