Protein Alignment Dronc and casp8

DIOPT Version :9

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_005165894.1
• Gene: casp8 / 58022
• ZFINID: ZDB-GENE-000713-1
• Length: 477
• Species: Danio rerio
• Alignment Length: 486
• Identity: 101/486 - (20%)
• Similarity: 178/486 - (36%)
• Gaps: 121/486 - (24%)

  Fly    10 MPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQML------------------RNTQDLN 56
            :|||..|.:          |:.:.|.:...:||:|..::|                  ::.:::.
Zfish    29 IPKRRLESV----------TDAKDLILRLDEQGLLEDELLFPELLITIGRIDLLEILKKSKEEVK 83

  Fly    57 GKPFNMDEKDVRVEQHRRLLLKI----TQRGPTAYNLLINAL-----RNINCLDAAVLLES---- 108
            ......|.....|..:|::||||    |:....|...|::..     |:.:.||..:.:|.
Zfish    84 RNLLRCDNSRKGVSAYRKMLLKISEDMTEENFRAAKFLLDLPRAKLGRSTSFLDTLIEMEKQQRL 148

  Fly   109 -----------VDESDSRPPFISLNERRTSRKSAD-----------IVDTPSPEASEGPCVSKLR 151
                       :::.|.:...:....|..|.:..:           .::.|..|..|.   .:.|
Zfish   149 GPDNLDELYRILEKCDKQLAVMIERFRNQSHRDQEQVGGRLPLEEVFLNNPVSETMER---ERRR 210

  Fly   152 NEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMVNIMDYPDQNR--RRI 214
            |...|.:|........|                ..|.:.::...|..|::|..::.....  :|.
Zfish   211 NSSAGTITTDAETPLNP----------------NEYYILTQRPLGYCLIINNYNFLKSTNLLKRT 259

  Fly   215 GAEKDSKSLIHLFQELNFTIFPYGNVNQD-----------QFFKLLTMVTSSSYVQNTECFVMVL 268
            |.:.|...|..||..::|.|    .|..|           ||        ::....:...||..:
Zfish   260 GTDMDKDRLAKLFSRMHFQI----EVRSDLEAWAIKDEIKQF--------ANKNHASMGAFVCCI 312

  Fly   269 MTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGN 333
            ::||.    |..|...||..|:::::...|  |.|..|.:|||:.....|:|||...|...:.|.
Zfish   313 LSHGE----KGTVLGTDGKPVEIREVTLPF--AGCRTLASKPKLFFIQACQGDENQAGVWTSDGR 371

  Fly   334 LMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMA 398
            ...|   .::||:  .:..|| .....:|..||.|:..|....|:::|....||.:||:.|:.|.
Zfish   372 EDAP---EEDEKY--EEDAGI-IVLRKIPIEADFLIGMATVEHYLSYRHTKEGSIFIQELCKKME 430

  Fly   399 DHA-HDTDLEDILKKTSEAVGNKRTKKGSMQ 428
            :.. ...|:..||.|.:..| :||..||..|
Zfish   431 ELCPKKEDMLSILTKVNFEV-SKRILKGYKQ 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	19/114 (17%)
		CASc	186..443	CDD:237997	66/257 (26%)
casp8	XP_005165894.1	DED_Caspase_8_10_r1	2..76	CDD:260059	10/56 (18%)
		DED_Caspase_8_10_r2	96..176	CDD:260042	14/79 (18%)
		CASc	230..475	CDD:237997	66/256 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587222
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740