Protein Alignment Dronc and casp23

DIOPT Version :10

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001103182.1
• Gene: casp23 / 563034
• ZFINID: ZDB-GENE-071004-27
• Length: 446
• Species: Danio rerio
• Alignment Length: 467
• Identity: 96/467 - (20%)
• Similarity: 162/467 - (34%)
• Gaps: 146/467 - (31%)

  Fly     8 IGMPKRHREHIRKNLNIL-----------------VEWTNYERLAMECVQQGILTVQMLRNTQDL 55
            |.:..:.||.:.:||..:                 ||..|...|.::|.   |.|.
Zfish    97 IPLSDKQREFLEENLAAIVARRLFDFKSCPGCQSHVERRNRNNLCVKCT---ICTA--------- 149

  Fly    56 NGKPFNMDEKDVRVEQHRRLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFIS 120
                 ||.:......:.||....:|              .|..|.......:||.|.|...|.
Zfish   150 -----NMTQTYYFCWKCRREWKGVT--------------NNAECCGNTGCGQSVTEPDPLKPC-- 193

  Fly   121 LNERRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILG 185
                 ||...|:.:.|      ||.|:..::::             .|:.|:
Zfish   194 -----TSEFKAEKLMT------EGKCIYPVKDK-------------SPQRKR------------- 221

  Fly   186 TYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVN-QDQFFKLL 249
                       :.|::|.:|:.|  ..|.||:||..|:..|.:.|.:::....::: |.....:.
Zfish   222 -----------LALLINNVDFKD--NVRTGADKDELSMERLLKGLGYSVVTLRDLSAQGMSTAMR 273

  Fly   250 TMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHF---------QTAKCPY 305
            .......:..:..||| |||:||      ::...|  .:.|.....|.|         .|..|..
Zfish   274 DFSQRKEHADSDSCFV-VLMSHG------DESGIC--GIFDSSSQDDVFPPDEIFKCLNTPNCAG 329

  Fly   306 LVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVC 370
            |.:|||:::...|||     |.|   ||:..|              :.:|...|..........|
Zfish   330 LRDKPKIILIQSCRG-----GKP---GNVDVP--------------DSVPIRGTRREHKEKDFCC 372

  Fly   371 Y-ANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDN 434
            : ::||..|::|:.:.||.:||...::...||::.|:|::.:|    |..|..:....|....:.
Zfish   373 FRSSTPDTVSYRNKEKGSHFIQDLVEIFNRHAYEDDIEELFRK----VIMKFRETHDEQMPCKER 433

  Fly   435 LGFNKKLYFNPG 446
            ....||.|..||
Zfish   434 TTLCKKFYLFPG 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	16/104 (15%)
		CASc	186..443	CDD:237997	60/267 (22%)
casp23	NP_001103182.1	BRcat_Rcat_RBR	123..>166	CDD:459240	11/59 (19%)
		CASc	210..444	CDD:444667	63/307 (21%)