Protein Alignment Dronc and casp10

DIOPT Version :9

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_685430.4
• Gene: casp10 / 557302
• ZFINID: ZDB-GENE-070608-2
• Length: 520
• Species: Danio rerio
• Alignment Length: 436
• Identity: 99/436 - (22%)
• Similarity: 183/436 - (41%)
• Gaps: 57/436 - (13%)

  Fly    20 KNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRRLLLKITQRGP 84
            ||:..|:..|    |:.:.::|.:..:|:.          ..|:::|:..|.:..:|.:|.....
Zfish   128 KNIKFLLMKT----LSRKKLEQNLTLLQLF----------LEMEKEDLLGENNLDVLQRIFADIY 178

  Fly    85 TAYNLLINALR--NINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPSPEASEGPCV 147
            .|....||..:  |:|.:..|      .|::.......|...:||..|.:::|....|.:.....
Zfish   179 PALGRKINQYKEENLNGVFIA------QETEGISSIADLPSAQTSLSSVEMIDREMDEITLNENA 237

  Fly   148 SKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMVNIMDYPD---Q 209
            |...    |..:.:...|:...:.:|.::...:::::..|:|:.. .|||.|::|..|:..   .
Zfish   238 SGFS----GDNSQHSDSVNSGIISESSEMPQIENSMVEQYEMKGE-RRGVCLIINNYDFSACGWL 297

  Fly   210 NRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHG-- 272
            ||.  |.:.|..||..:|:.|.|.|....:...||..:.|..:::..:.| .:|.|..:::||
Zfish   298 NRE--GTDIDHDSLRDVFEWLGFEILTRRDCTGDQILQALMDLSTQDHTQ-ADCVVCCILSHGRL 359

  Fly   273 NSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEP 337
            |.:.|      .||..|..:::.:.....:|..|..|||:.....|||.:       ||..:...
Zfish   360 NDIIG------VDGKAVPFKELMETLSPFRCSSLYQKPKLFFIQACRGTQ-------NQRAVFPQ 411

  Fly   338 VYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFC---QVMAD 399
            .:|..|:..  ....|:|..|  :|.:||.|:..:..|.|.::||...|:|:||..|   :::..
Zfish   412 TFTEDEDVL--ASDAGVPRDS--IPEMADYLMAMSTVPWYASYRDKSKGTWFIQSLCDNLRLLVP 472

  Fly   400 HAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFNKKLYFNP 445
            ..:  ||..||.|.:..|..|..|.|..:..........:.:.|.|
Zfish   473 RGN--DLLSILTKVNADVSKKSDKSGLKKQMPQPEFSLTRTVVFPP 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	18/87 (21%)
		CASc	186..443	CDD:237997	68/264 (26%)
casp10	XP_685430.4	DED_Caspase_8_10_r1	11..87	CDD:260059
		DED_Caspase_8_10_r2	108..190	CDD:260042	15/75 (20%)
		DUF4603	<200..>256	CDD:292020	10/59 (17%)
		CASc	273..515	CDD:237997	68/264 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810