DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dronc and casp7

DIOPT Version :9

Sequence 1:	NP_524017.1	Gene:	Dronc / 39173	FlyBaseID:	FBgn0026404	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001018443.1	Gene:	casp7 / 553634	ZFINID:	ZDB-GENE-050522-506	Length:	316	Species:	Danio rerio

Alignment Length:	275	Identity:	70/275 - (25%)
Similarity:	118/275 - (42%)	Gaps:	46/275 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 YKMQSRFNRGVLLMVNIMDYPDQNRRRI--GAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLL 249
            ||| |....|..:::|..::.::....:  |.::|:..|...|:.|.|.:..|.:.......:||
Zfish    71 YKM-SHQRVGKCIIINNKNFDEKTGMNVRNGTDRDAGELFKCFKSLGFDVAVYNDQTCRNMERLL 134

  Fly   250 TMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLM 314
            ..|:...: .::.||..:|::||.  ||  .:...||: :.::.:...|:...|..||.|||:..
Zfish   135 KAVSEEDH-SDSSCFACILLSHGE--EG--MIYGTDGA-MPIKTMTSLFKGDVCKSLVGKPKLFF 193

  Fly   315 FPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVT 379
            ...|||.|:|.|...:.|.             |:...|...:|...:|..||.|..|:..|||.:
Zfish   194 IQACRGSEFDDGVQTDSGP-------------PNDTIETDANPRHKIPVEADFLFAYSTVPGYYS 245

  Fly   380 HRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNK----------RTKKG-----SMQT 429
            .|:...|||::|..|.|:::.....::..||.:.:..|...          ..||.     ||.|
Zfish   246 WRNPGRGSWFVQALCNVLSEFGKQLEIMQILTRVNYMVATSFESWSEDPRFSEKKQIPCVVSMLT 310

  Fly   430 GAYDNLGFNKKLYFN 444
                     |:||||
Zfish   311 ---------KELYFN 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018
Dronc	NP_524017.1	CASc	186..443	CDD:237997	67/272 (25%)
casp7	NP_001018443.1	CASc	71..315	CDD:237997	67/272 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910