Protein Alignment Dronc and casp9

DIOPT Version :10

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001007405.2
• Gene: casp9 / 492763
• ZFINID: ZDB-GENE-030825-5
• Length: 436
• Species: Danio rerio
• Alignment Length: 468
• Identity: 119/468 - (25%)
• Similarity: 199/468 - (42%)
• Gaps: 71/468 - (15%)

  Fly    10 MPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRR 74
            |.::||:.::::...||:..|.|.:..:.:.:|:.|..|:...|          .|..|.:|.|:
Zfish     1 MEQKHRQILQRHRLNLVKALNPEDVCDKLLSKGVFTQDMIDEIQ----------SKATRRDQARQ 55

  Fly    75 LLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPSP 139
            |:..:..||..|:...:::||.....|.|.||:|.| ...|||.||:..........::..|..|
Zfish    56 LVKDLETRGSLAFPAFLDSLRETGHNDLAELLQSGD-GVHRPPVISVQPSPIPLPVQNLNHTEKP 119

  Fly   140 EASE--GPCVSKLRNEPL---GALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLL 199
            :..:  .|.:..||.|.|   ...:|....|..|...:...|.        .|||.:. ..||.|
Zfish   120 DKPDIASPRLVPLRPESLPVHKTYSPPSETVVRPTRPRRDSIQ--------CYKMDAS-PCGVCL 175

  Fly   200 MVNIMDY---PDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQF---FKLLTMVTSSSYV 258
            ::|.:::   .:.|.|: |:..|...|...|:.|||.:....|:...:.   ...|.....|:|
Zfish   176 IINNINFEKASELNDRK-GSNIDCDKLEKRFKALNFEVTVKRNLKSKRIRHEMASLAKKDHSTY- 238

  Fly   259 QNTECFVMVLMTHGNSVEGKE---KVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRG 320
               :|.|:::::||.......   .|...||..|.:|.|.::.....||.|..|||:.....|.|
Zfish   239 ---DCCVVIILSHGTEASHNRFPGAVHGVDGPAVPIQIITNYLNGQNCPSLQGKPKLFFIQACGG 300

  Fly   321 DEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPST---------------NVPSLADTLVC 370
            .|.|:|...:..::...:...      |.:.:.||..|:               ::|:.:|.||.
Zfish   301 GEKDIGFEVSPDDVQPSIGGI------DDEMDAIPMSSSSDSLSTASDELDARASLPTPSDILVS 359

  Fly   371 YANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNL 435
            |:..||||:.||.:.||||::...:|:.::|...||..:|...::||.....|      |.|..:
Zfish   360 YSTFPGYVSWRDTEAGSWYVENLDRVLEENAITDDLVTMLMLVNDAVSQISAK------GLYKQM 418

  Fly   436 --GFN---KKLYF 443
              .||   |.|||
Zfish   419 PGSFNFLRKLLYF 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	20/87 (23%)
		CASc	186..443	CDD:237997	74/285 (26%)
casp9	NP_001007405.2	CARD_CASP9	5..88	CDD:176740	23/92 (25%)
		CASc	163..432	CDD:237997	76/287 (26%)