DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dronc and Decay

DIOPT Version :9

Sequence 1:	NP_524017.1	Gene:	Dronc / 39173	FlyBaseID:	FBgn0026404	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_477462.1	Gene:	Decay / 42008	FlyBaseID:	FBgn0028381	Length:	308	Species:	Drosophila melanogaster

Alignment Length:	246	Identity:	66/246 - (26%)
Similarity:	112/246 - (45%)	Gaps:	35/246 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 TYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLT 250
            ||:..:|  .|:.|::|..|...| ::|:|.|:|...:....|...|.:..:.::...:....|.
  Fly    48 TYENCAR--AGIALILNHKDVKGQ-KQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLK 109

  Fly   251 MVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMF 315
            .|....:.|| :|||:.:|:||  .|||   .:.......::::.:.|....|..|.||||:...
  Fly   110 EVAREDHSQN-DCFVLAVMSHG--TEGK---VYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFI 168

  Fly   316 PFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNV-------PSLADTLVCYAN 373
            ..|||           .||.:.|   :...:.....|.:|.|:..|       ||.||.||.|:.
  Fly   169 QACRG-----------ANLEKAV---EFSSFAVMTRELVPEPAAAVQPITYAIPSTADILVFYST 219

  Fly   374 TPGYVTHRDLDTGSWYIQKFCQVM----ADHAHDTDLEDILKKTSEAVGNK 420
            ...:.:.|::|.|||:||..|:|:    |:.|...:..::|:..: ||..|
  Fly   220 FDKFFSFRNVDDGSWFIQSLCRVLDQAAANEAATPEGVELLRLLT-AVNRK 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018
Dronc	NP_524017.1	CASc	186..443	CDD:237997	66/246 (27%)
Decay	NP_477462.1	CASc	54..302	CDD:237997	64/240 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450669
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840