Protein Alignment Dronc and casp2

DIOPT Version :10

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_005157976.1
• Gene: casp2 / 373118
• ZFINID: ZDB-GENE-030825-3
• Length: 437
• Species: Danio rerio
• Alignment Length: 480
• Identity: 117/480 - (24%)
• Similarity: 196/480 - (40%)
• Gaps: 87/480 - (18%)

  Fly     7 EIGMPKRHREHIRKNLNILVEWTNYERLAMECVQQ-GILTVQMLRNTQDLNGKPFNMDEKDVRVE 70
            |.||.|..|..:|:|...:::....:.|.::|:|| ||||..|   .:.:..||.:..
Zfish     4 ECGMTKWERLALRRNSVKMLQDLVVDDLLIQCLQQDGILTDSM---AESIMAKPTSQG------- 58

  Fly    71 QHRRLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDS--RPPFISL---------NER 124
            :..:||..:.:|||.|::...:||:.........||....|.|.  ..|.:||         ...
Zfish    59 RSHQLLFLLPKRGPRAFSTFCSALKETEQHHLCKLLMDFTEKDKCFSEPSLSLPTQECVTPAKRP 123

  Fly   125 RTSRKSADIVDTPSPEASEG-PCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYK 188
            ||.......:|..||..:.. ||.                    ||..:|.:..        .|.
Zfish   124 RTHESMEMCLDADSPVTTAVLPCT--------------------PEFYQSHRPQ--------AYP 160

  Fly   189 MQSRFNRGVLLMVNIMDYPDQNRR---RIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLT 250
            |:| ..||:.|:::.:.:...|..   |.|.|.|.::|..||.||:|.:..:.::..:...:.|.
Zfish   161 MRS-CPRGLALVLSNVRFDSANTDLDIRRGGEVDEETLRRLFTELDFKVSLHRDLTAEAMRRCLE 224

  Fly   251 MVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMF 315
            ...........:|.|:.|::||  |||  .|...||.::::..:.:.|..|:||.|.||||:...
Zfish   225 QFAQQQEHAAYDCAVVCLLSHG--VEG--SVYGTDGQLLELDWVFEVFDNARCPLLQNKPKMFFI 285

  Fly   316 PFCRGDEYDL------GHPKNQGNLMEPVYTAQE------EKWPDTQTEGIPSPSTNVPSLADTL 368
            ..|||:|.|.      |..:.|....|.....:|      ||..:.:.|.:   ...:|..:|.:
Zfish   286 QACRGEEMDNGVDQLDGQERTQSPGCEQRDAGREGERDNREKKEEKERERL---RVKLPQRSDMI 347

  Fly   369 VCYANTPGYVT--HRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGA 431
            ..:|...|:.|  .|:...|||:||:....:...|::|.|.|||.:.:   |..::::|.....|
Zfish   348 CGFATLKGFSTAAMRNTKKGSWFIQELNTAIRQRANNTHLSDILVQVN---GQIKSREGYAPGSA 409

  Fly   432 YDNL--------GFNKKLYFNPGFF 448
            :...        ...|.||..|.::
Zfish   410 HHRCKEMSEFTSSLCKDLYLFPKYY 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	21/88 (24%)
		CASc	186..443	CDD:237997	72/281 (26%)
casp2	XP_005157976.1	CARD_CASP2	7..94	CDD:260040	24/96 (25%)
		CASc	158..430	CDD:237997	73/282 (26%)