DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dronc and Damm

DIOPT Version :9

Sequence 1:	NP_524017.1	Gene:	Dronc / 39173	FlyBaseID:	FBgn0026404	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001303345.1	Gene:	Damm / 36266	FlyBaseID:	FBgn0033659	Length:	255	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	58/247 - (23%)
Similarity:	100/247 - (40%)	Gaps:	43/247 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 MVNIMDYP-DQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTEC 263
            ::|...:| |....|.|:..|..:|...|:.|...:....|.........:...::..:.|:..
  Fly    42 ILNHEQFPQDSQLNRKGSSNDVNALRKTFESLKCRVEVISNPALPDVKNKVKEWSAKRFTQDAG- 105

  Fly   264 FVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDH--FQTAKCPYLVNKPKVLMFPFCRGDEYDLG 326
            ||:.:::||   :.|||:..||.....:.   |.  |...:.|.|..|||:|:...|:|
  Fly   106 FVLFILSHG---DRKEKILACDHREYHLD---DDVLFPLFRNPTLSGKPKILIVQACKG------ 158

  Fly   327 HPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQ 391
                      |: .|..:|            ..|.|.:.    ||:.:.||:::|:.:.||.:||
  Fly   159 ----------PL-RADAKK------------MNNEPYIK----CYSCSEGYLSYRNENHGSVFIQ 196

  Fly   392 KFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFNKKLYF 443
            ..|:.|..:....|.:.|.|.....|..:.|..||.|..:.::..|:|..||
  Fly   197 TLCEAMDQYGLTRDFQSIFKHVKAEVERRSTMTGSKQVPSEESHNFDKPFYF 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018
Dronc	NP_524017.1	CASc	186..443	CDD:237997	56/245 (23%)
Damm	NP_001303345.1	Peptidase_C14	42..248	CDD:279049	56/245 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810