DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dronc and Casp14

DIOPT Version :9

Sequence 1:	NP_524017.1	Gene:	Dronc / 39173	FlyBaseID:	FBgn0026404	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001178705.1	Gene:	Casp14 / 299587	RGDID:	1311781	Length:	246	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	61/242 - (25%)
Similarity:	100/242 - (41%)	Gaps:	38/242 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 RRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLT--MVTSSSYVQNTECFVMVLMTHGN 273
            :.|.|:|.|..:|..:||.|.|......:....||...:.  ..|..::.:...|..:|||.||.
  Rat    31 KAREGSEVDMDALERMFQYLKFESTMKRDPTAQQFLDDMDEFQQTIENWKEPVSCAFVVLMAHGE 95

  Fly   274 SVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPV 338
              ||..|.|  ||::|.::.:.:......|..|..||||.:...|||:..|.|
  Rat    96 --EGFLKGE--DGNMVRLEDLFEVLNNKNCKALRGKPKVYIIQACRGEHRDPG------------ 144

  Fly   339 YTAQEEKWPDTQTEGI--PSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHA 401
                 |:.|..:...|  .:|.| :|:..|.:..|:...|::::|....||.:||....|.. |.
  Rat   145 -----EELPGDELAVIKKKNPPT-IPTYTDMIHIYSTVEGFLSYRHDQKGSGFIQTLTDVFI-HK 202

  Fly   402 HDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLG------FNKKLY 442
            ..: :.::|::.:..:.|...    ||.|....:.      ..||||
  Rat   203 KGS-ITELLEEITRLMANTEV----MQEGKPRKVNPEIQSTLRKKLY 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018
Dronc	NP_524017.1	CASc	186..443	CDD:237997	61/242 (25%)
Casp14	NP_001178705.1	CASc	10..246	CDD:237997	61/242 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346266
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1092723at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950