Protein Alignment Dronc and Casp1

DIOPT Version :9

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_036894.3
• Gene: Casp1 / 25166
• RGDID: 2274
• Length: 402
• Species: Rattus norvegicus
• Alignment Length: 419
• Identity: 98/419 - (23%)
• Similarity: 174/419 - (41%)
• Gaps: 74/419 - (17%)

  Fly    55 LNGKPFNMDEKD-------VRVEQHRRLLLKITQRGPTAYNLLINALRNINCLDAAVL-LES--- 108
            |..:..|.:|.|       ..:|:.|.|...:|::||.|..:.|..:.|.:|..|.:| |:|
  Rat    30 LEKRVLNQEEMDTIKLANITVMEKARDLCDHVTKKGPRASQMFITYICNEDCYLAEILELQSGPS 94

  Fly   109 ------VDESDSRPPFISLNERRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDG 167
                  .::|....||.|..:.:.:::....   |.|..|...|..::..
  Rat    95 AETVFVTEDSKGGHPFSSETKEKLNKEGGAF---PGPSGSLKFCPLEIAQ--------------- 141

  Fly   168 PEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNF 232
               |..|:.|   |.|....|..:| .|..|::.| .|:...: ||:||:.|.:.:..|.|:|.:
  Rat   142 ---KLWKENH---SEIYPIMKTPTR-TRLALIICN-TDFQHLS-RRVGADVDLREMKLLLQDLGY 197

  Fly   233 TIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDH 297
            |:....|:...:..|.|....:....:.::...:|.|:||.. ||...:.: ...|.|:.|:...
  Rat   198 TVKVKENLTALEMTKELKEFAACPEHKTSDSTFLVFMSHGLQ-EGICGITY-SNEVADILKVDTI 260

  Fly   298 FQ---TAKCPYLVNKPKVLMFPFCRGDEY-------DLGHPKNQGNLMEPVYTAQEEKWPDTQTE 352
            ||   |.|||.|.:||||::...|||::.       .:|: ..:|.|.:.::          :.:
  Rat   261 FQMMNTLKCPSLKDKPKVIIIQACRGEKQGVVLLKDSVGN-SEEGFLTDAIF----------EDD 314

  Fly   353 GIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAV 417
            ||......    .|.:...::||..|:.|....||.:|:...:.|.::|...|||||.:|...:.
  Rat   315 GIKKAHIE----KDFIAFCSSTPDNVSWRHPVQGSLFIESLIKHMKEYAWSCDLEDIFRKVRFSF 375

  Fly   418 GNKRTKKGSMQTGAYDNLGFNKKLYFNPG 446
            ....::   :|....:.:...|:.|..||
  Rat   376 EQPDSR---LQMPTTERVTLTKRFYLFPG 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	16/58 (28%)
		CASc	186..443	CDD:237997	64/266 (24%)
Casp1	NP_036894.3	CARD_CASP1-like	6..87	CDD:260036	15/56 (27%)
		CASc	152..400	CDD:214521	65/270 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346264
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700