Protein Alignment Dronc and Dronc

DIOPT Version :10

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_318061.4
• Gene: Dronc / 1278470
• VectorBaseID: AGAMI1_004991
• Length: 430
• Species: Anopheles gambiae
• Alignment Length: 477
• Identity: 137/477 - (28%)
• Similarity: 233/477 - (48%)
• Gaps: 91/477 - (19%)

  Fly    10 MPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRR 74
            |..:.|..|..|:..||.:|||::|:.||:||.:|:..|:...:.:     ..||    |.:|::
Mosquito     1 MNNKDRFLITHNVEKLVNYTNYKQLSFECIQQKMLSPTMVSRIEGI-----AQDE----VTRHKK 56

  Fly    75 LLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPSP 139
            |..|||:|||.|::.|:...:  .....|.|:...:.:|:: ...:.|.:|....|.::
Mosquito    57 LFEKITKRGPKAFDTLLAICQ--QAFPTAYLILKPNSNDNQ-MHSTHNPQRVRSVSCNV------ 112

  Fly   140 EASEGPCVSKLRNEPLGALTPYVGVVDGPE---------VKKSKKIHGGDSAILGT--------- 186
                .|.|..||:.         |.||..:         |::||.|......||.|
Mosquito   113 ----APKVYSLRSP---------GDVDDGKNNNFASNALVEESKCILQVYPDILPTTFSVKLSTR 164

  Fly   187 ----------YKMQSRFNRGVLLMVNIMDY-----PDQNRRRIGAEKDSKSLIHLFQELNFTIFP 236
                      |.|:.| ||||..:||::.:     |.:|    ||:.|.::||.:||:|.|.:|.
Mosquito   165 PAETHPKVPAYPMKGR-NRGVAFIVNVITFLKKVHPTRN----GADIDGRNLISVFQQLGFVVFY 224

  Fly   237 YGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTA 301
            |.::......:||..:..|.:: :.:||...:::||:..:|.:.:...|.|::.::.:...|.:.
Mosquito   225 YEDITMGDLKELLAQLKESEHL-SCDCFAFYILSHGDHRKGSDYIFLHDNSLLRVEDLLTEFNSV 288

  Fly   302 KCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGN-----LMEPVYTAQEEKWPDTQTEGIPSPSTNV 361
            .|..||:|||:.....|||.:.|||..:...|     :::|               |.|.|| |:
Mosquito   289 NCKRLVHKPKLFFISICRGVQSDLGAYRLSTNTERDGMIDP---------------GKPLPS-NI 337

  Fly   362 PSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGS 426
            .:..|.|||||..||:..|||.:||||:::..|::.::||||||:|.::|...|...:.||:..:
Mosquito   338 ATYCDMLVCYATVPGFAAHRDTNTGSWFVESMCKIWSEHAHDTDVEILMKLVGEYASSYRTEHSA 402

  Fly   427 MQTGAYDNLGFNKKLYFNPGFF 448
            :||...:..||.|:|:.|||::
Mosquito   403 LQTICTEQRGFFKQLFLNPGYY 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	28/87 (32%)
		CASc	186..443	CDD:237997	86/285 (30%)
Dronc	XP_318061.4	CARD	9..78	CDD:260018	25/68 (37%)
		CASc	174..388	CDD:444667	71/242 (29%)