DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dronc and Casp14

DIOPT Version :9

Sequence 1:	NP_524017.1	Gene:	Dronc / 39173	FlyBaseID:	FBgn0026404	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_033939.1	Gene:	Casp14 / 12365	MGIID:	1335092	Length:	257	Species:	Mus musculus

Alignment Length:	245	Identity:	65/245 - (26%)
Similarity:	105/245 - (42%)	Gaps:	33/245 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 RRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLT--MVTSSSYVQNTECFVMVLMTHGN 273
            :.|.|:|.|.::|..:|:.|.|......:....||.:.|.  ..|..::.:...|..:|||.||.
Mouse    31 KAREGSEVDMEALERMFRYLKFESTMKRDPTAQQFLEELDEFQQTIDNWEEPVSCAFVVLMAHGE 95

  Fly   274 SVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPV 338
              ||..|.|  |..:|.::.:.:......|..|..||||.:...|||:..|.|. :.:||
Mouse    96 --EGLLKGE--DEKMVRLEDLFEVLNNKNCKALRGKPKVYIIQACRGEHRDPGE-ELRGN----- 150

  Fly   339 YTAQEEKWPDTQTEG-----IPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMA 398
                ||...|.:..|     :.:...::|:..|||..|:...||:::|..:.||.:||....|..
Mouse   151 ----EELGGDEELGGDEVAVLKNNPQSIPTYTDTLHIYSTVEGYLSYRHDEKGSGFIQTLTDVFI 211

  Fly   399 DHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLG------FNKKLY 442
             |...:.|| :.::.:..:.|...    ||.|....:.      ..||||
Mouse   212 -HKKGSILE-LTEEITRLMANTEV----MQEGKPRKVNPEVQSTLRKKLY 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018
Dronc	NP_524017.1	CASc	186..443	CDD:237997	65/245 (27%)
Casp14	NP_033939.1	CASc	10..257	CDD:237997	65/245 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1092723at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.810