Protein Alignment Dronc and Casp12

DIOPT Version :9

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_036010474.1
• Gene: Casp12 / 12364
• MGIID: 1312922
• Length: 425
• Species: Mus musculus
• Alignment Length: 412
• Identity: 86/412 - (20%)
• Similarity: 151/412 - (36%)
• Gaps: 75/412 - (18%)

  Fly    76 LLKITQRGPTAYNLLINALRNI----------------NCLDAAVLLESVDESDSRPPFISLNER 124
            ||||.:......|...|.:.|.                |..:...|..|.||.|......:.:..
Mouse    47 LLKIGESASFILNKAENLVENFLEKTDMAGKIFAGHIANSQEQLSLQFSNDEDDGPQKICTPSSP 111

  Fly   125 RTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGD--------- 180
            ..|::.   |:....|.:.|     |.:|....||...| :...||:.:.|:...|
Mouse   112 SESKRK---VEDDEMEVNAG-----LAHESHLMLTAPHG-LQSSEVQDTLKLCPRDQFCKIKTER 167

  Fly   181 -SAILGTYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQ 244
             ..|....:.:.|....:::.....||...   |..|:.|..::..|.:.|.:::....|:...:
Mouse   168 AKEIYPVMEKEGRTRLALIICNKKFDYLFD---RDNADTDILNMQELLENLGYSVVLKENLTAQE 229

  Fly   245 FFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEG----KEKVEFCDGSVVDMQKIKDHFQTAKCPY 305
            ....|.........|:::...:|.|:|| .:||    |.:.:..|  |:....|...|..:.|..
Mouse   230 METELMQFAGRPEHQSSDSTFLVFMSHG-ILEGICGVKHRNKKPD--VLHDDTIFKIFNNSNCRS 291

  Fly   306 LVNKPKVLMFPFCRGDEYD--LGHPKNQGNLMEPVYTAQEE-------KWPDTQTEGIPSPSTNV 361
            |.||||:|:...||| .|:  :....|:|     :.||..:       ||.::.|:      .:|
Mouse   292 LRNKPKILIMQACRG-RYNGTIWVSTNKG-----IATADTDEERVLSCKWNNSITK------AHV 344

  Fly   362 PSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEA--VGNKRTKK 424
            .:  |.:...::||..::.:...|||.:|.|.......:.....||:|.:|...:  |..:.|
Mouse   345 ET--DFIAFKSSTPHNISWKVGKTGSLFISKLIDCFKKYCWCYHLEEIFRKVQHSFEVPGELT-- 405

  Fly   425 GSMQTGAYDNLGFNKKLYFNPG 446
               |....:.:...:..|..||
Mouse   406 ---QMPTIERVSMTRYFYLFPG 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	8/45 (18%)
		CASc	186..443	CDD:237997	56/271 (21%)
Casp12	XP_036010474.1	CARD_CASP1-like	12..94	CDD:260036	9/46 (20%)
		CASc	172..423	CDD:214521	57/275 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842789
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700