Protein Alignment Dronc and CASP12

DIOPT Version :9

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001177945.2
• Gene: CASP12 / 100506742
• HGNCID: 19004
• Length: 341
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 53/251 - (21%)
• Similarity: 92/251 - (36%)
• Gaps: 41/251 - (16%)

  Fly   213 RIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHG--NSV 275
            |.|:|.|...:..|.:.|.:::....|:...:....|....:....|:::...:|.|:|.  |.:
Human   114 RNGSELDLLGMRDLLENLGYSVVIKENLTAQEMETALRQFAAHPEHQSSDSTFLVFMSHSILNGI 178

  Fly   276 EGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGD-------EYDLGHPKN--- 330
            .|.:..: .:..|:....|.:.|....|..|.:||||::...|||:       ..|.|....
Human   179 CGTKHWD-QEPDVLHDDTIFEIFNNRNCQSLKDKPKVIIMQACRGNGAGIVWFTTDSGKASADTH 242

  Fly   331 ----QGNLMEPVYT-AQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYI 390
                |||:.....| |..||                    |.:...::||..|:.|....||.:|
Human   243 GRLLQGNICNDAVTKAHVEK--------------------DFIAFKSSTPHNVSWRHETNGSVFI 287

  Fly   391 QKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFNKKLYFNPG 446
            .:......:::....||:|.:|...:.   .|.....|....:.|...:..|..||
Human   288 SQIIYYFREYSWSHHLEEIFQKVQHSF---ETPNILTQLPTIERLSMTRYFYLFPG 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018
		CASc	186..443	CDD:237997	50/246 (20%)
CASP12	NP_001177945.2	CARD_CASP1-like	6..88	CDD:260036
		CASc	103..339	CDD:214521	51/248 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840