Protein Alignment Dronc and casp8

DIOPT Version :10

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_017953067.2
• Gene: casp8 / 100495471
• XenbaseID: XB-GENE-487755
• Length: 507
• Species: Xenopus tropicalis
• Alignment Length: 459
• Identity: 106/459 - (23%)
• Similarity: 192/459 - (41%)
• Gaps: 85/459 - (18%)

  Fly    16 EHIRKNLNILVEWTNYERLAMECVQQGILTVQM--LRNTQDLN-GKPFNMDEKDVRVEQHRRLLL 77
            |.:::.:.|..:.:.| |:.:..:.||:...|:  |:...:|: .|..|....|:.:|     |.
 Frog    98 EDMKQLIEISAQISPY-RILLHDISQGLSKKQVDDLKYLLNLSTAKTENAPILDIFLE-----LE 156

  Fly    78 KITQRGPTAYNLLINALRNINCLDAAVLLESVDES--------DSRPPF---ISLNERRTSRKSA 131
            |:.:..|....:|...|..|.|.:.:..:|..:.:        :|.|..   ||:.|.::
 Frog   157 KVGKLSPEDLQVLKYNLEAIGCKNLSKNIEDFERASEADNQGLESLPDLIEKISIQEEQS----- 216

  Fly   132 DIVDTPSPEASEG-PCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNR 195
               :....|||.| |.:.:...|.           |....::...|:      |.||:::.: ..
 Frog   217 ---NMTVQEASTGQPRLPQAETES-----------DSGRPQQHTHIN------LETYRLEKQ-PH 260

  Fly   196 GVLLMVNIMDYPDQNRR------RIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTS 254
            |..:::|..|:.:...|      |.|..||::.:..:|.|..:....:.::..:...|.|.|.:.
 Frog   261 GWCVVINNYDFREARSRDCKYSNREGTMKDAEDITKIFNERGYITEEHKDLTAENIRKTLEMYSK 325

  Fly   255 SSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCR 319
            ..:.:| :.||..:::||    |...|..|||..|:::::..:|....||.|:||||:.....|:
 Frog   326 KDHAEN-DSFVCFILSHG----GIGTVCGCDGEEVEIKRLTKYFNGQHCPSLINKPKIFFIQACQ 385

  Fly   320 GDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLD 384
            |.|   .|||...|      |..|..:...:.:.:   .|::|..||.|..:|....|.:.|.::
 Frog   386 GKE---SHPKVDIN------TDTESSFSFYEQDAM---GTHLPLEADFLTAFATVEEYTSLRHIE 438

  Fly   385 TGSWYIQKFCQVMADHAHDTDLEDILKKTSEAV-------GNKR-TKKGSMQTGAYDNLGFNKKL 441
            .||.|||:.|:.:..|... ||.|:|...:..|       |.|. |:..|.::      ...|||
 Frog   439 KGSIYIQQLCKALTTHLCQ-DLIDMLTFVNNEVAGMLFPLGRKNVTQMPSFKS------ELRKKL 496

  Fly   442 YFNP 445
            ...|
 Frog   497 VLPP 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	19/90 (21%)
		CASc	186..443	CDD:237997	70/270 (26%)
casp8	XP_017953067.2	DD	18..98	CDD:472698	106/459 (23%)
		DD	110..190	CDD:472698	19/85 (22%)
		CASc	252..499	CDD:237997	70/271 (26%)