Protein Alignment Dronc and casp2

DIOPT Version :10

• Sequence 1: NP_524017.1
• Gene: Dronc / 39173
• FlyBaseID: FBgn0026404
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_012809163.2
• Gene: casp2 / 100486813
• XenbaseID: XB-GENE-482390
• Length: 421
• Species: Xenopus tropicalis
• Alignment Length: 412
• Identity: 100/412 - (24%)
• Similarity: 169/412 - (41%)
• Gaps: 36/412 - (8%)

  Fly     9 GMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHR 73
            ||.|.|::.:::....|:.....|.|....|..|||| .::.:|...:...:         :|:.
 Frog     4 GMQKHHKDALQRLRVTLLHDMIIEELVEHLVSSGILT-PIMHSTIMAHRSEY---------KQNV 58

  Fly    74 RLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPS 138
            .||.::.:|||.|::...|||   :......|.|.::|...:....|:......|.....|...:
 Frog    59 TLLTQLPKRGPRAFSEFCNAL---HATGQRHLAEQLEEEAQQQQMESVTPEVHERSFPLPVQEST 120

  Fly   139 PEASEGPCVSKLRNEPL--GALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMV 201
            |.........:...|.:  |         |||...:...:....|.....|||.| ..||..|::
 Frog   121 PSRPRRQFCREYNEESIDDG---------DGPGTVQLCSVDFYLSHHQQAYKMHS-CPRGRALII 175

  Fly   202 NIMDYPDQN-RRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFV 265
            :.:.:..|: ..|.|.|.|..||..||..|.|.:....|:|.......|...::.......:..|
 Frog   176 SNVAFETQDLDHRYGGEVDVASLEKLFSSLGFQVEVRRNLNAQNMMSQLGAFSALPAHSALDSCV 240

  Fly   266 MVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKN 330
            :.:::||  ::|  .|...||.:|.:|.:......|.||.|.||||:.....|||:|.|.|..:.
 Frog   241 VAVLSHG--LDG--AVYGTDGKLVQLQDVFTAMDNAHCPQLQNKPKMFFIQACRGEEADRGVDQR 301

  Fly   331 QGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQ 395
            .|.........::.   |...|.|   ...:|:.:|.:..||...|.|:.|:...|||::|....
 Frog   302 DGREQSASPGCEQS---DAGREDI---KVRLPTQSDMICAYACLKGTVSLRNTKRGSWFVQDLVS 360

  Fly   396 VMADHAHDTDLEDILKKTSEAV 417
            |.:.::.:|.:.|:|.|.:..:
 Frog   361 VFSQYSKNTHVADMLVKVNALI 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dronc	NP_524017.1	CARD	18..106	CDD:260018	19/87 (22%)
		CASc	186..443	CDD:237997	64/233 (27%)
casp2	XP_012809163.2	DD	5..86	CDD:472698	22/93 (24%)
		CASc	161..414	CDD:237997	64/233 (27%)