Protein Alignment nudE and NDEL1

DIOPT Version :10

• Sequence 1: NP_001097569.1
• Gene: nudE / 39169
• FlyBaseID: FBgn0036059
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: XP_016880672.1
• Gene: NDEL1 / 81565
• HGNCID: 17620
• Length: 390
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 111/304 - (36%)
• Similarity: 159/304 - (52%)
• Gaps: 37/304 - (12%)

  Fly     2 ESPPMFNSVEDECRYWKERSKQYHKEWTDVKQEYDEFVEQSREMEIEMDATLDQKQSIIKDLTAK 66
            |..|.|:|:::|..||||.|.:|.:.:.:.:.|..||.|.|||:|.|::|.|.|.:...:||.|.
Human    17 EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 81

  Fly    67 LTMFERENESLKLKLESHGI----DMSNMEKQLETVKKDRDTMKVYLRQLEQKNDDLERAHRILN 127
            ....:.|.|:||.|||....    .:|.:|..|...:..::.:..|:|:|||.|||||||.|...
Human    82 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 146

  Fly   128 ESIENFEKMLDQAYEKNALLELEVDEKGLLQEKLQRLMDETRDLKQELNVKSRFTPVV--NGTSV 190
            .|:|:||:.|:||.|:||.||.|:|||..|...:|||.||.|||:|||.|:.|...|.  :..|.
Human   147 VSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSS 211

  Fly   191 PTANDTNTVNSSMNSSASLPNGIVANGELVKHDNAVATRATSVSVNALNGSLVNRNEYNQQHSLK 255
            ||. |...::|::.:|.|||...|..|          |..|..|..|:
Human   212 PTL-DCEKMDSAVQASLSLPATPVGKG----------TENTFPSPKAI----------------- 248

  Fly   256 NPENQINGNSMNPSSRTTALNIVADMLRKLNWDKALLCPECEKF 299
              .|....:.:.||:|.:|||||.|:|||:...::.|. .|..|
Human   249 --PNGFGTSPLTPSARISALNIVGDLLRKVGALESKLA-ACRNF 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nudE	NP_001097569.1	GAS	<73..>167	CDD:464001	43/97 (44%)
		NUDE_C	129..>208	CDD:461464	37/80 (46%)
NDEL1	XP_016880672.1	Smc	<40..>208	CDD:440809	69/167 (41%)
		NUDE_C	148..322	CDD:461464	62/173 (36%)