Protein Alignment nudE and NDE1

DIOPT Version :10

• Sequence 1: NP_001097569.1
• Gene: nudE / 39169
• FlyBaseID: FBgn0036059
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: XP_006720960.1
• Gene: NDE1 / 54820
• HGNCID: 17619
• Length: 379
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 126/388 - (32%)
• Similarity: 191/388 - (49%)
• Gaps: 65/388 - (16%)

  Fly     2 ESPPMFNSVEDECRYWKERSKQYHKEWTDVKQEYDEFVEQSREMEIEMDATLDQKQSIIKDLTAK 66
            :|...|:|.|:|..|||:.:..|.:...:.::|..||.|.|||.|.|::..|.|.::..:||.::
Human    35 DSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 99

  Fly    67 LTMFERENESLKLKLE---SHGI-DMSNMEKQLETVKKDRDTMKVYLRQLEQKNDDLERAHRILN 127
            ......|.|::|.|.|   |.|. .:|.:|..|...|..:|.::.|:|:|||.|||||||.|...
Human   100 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATI 164

  Fly   128 ESIENFEKMLDQAYEKNALLELEVDEKGLLQEKLQRLMDETRDLKQELNV-----KSRFTPVVNG 187
            .|:|:||:.|:||.|:||.||.|:|||..|.|.:|||.||.|||:|||.|     |.|
Human   165 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPR------- 222

  Fly   188 TSVPTANDTNTVNSSMNSSASLPNGIVANGELVKHDNAVATRATSVSVNALNGSLVNRNEYNQQH 252
            |.:|::.:....::::.::.|:|:            ..:|.|..|.|:|. .||.
Human   223 TPMPSSVEAERTDTAVQATGSVPS------------TPIAHRGPSSSLNT-PGSF---------- 264

  Fly   253 SLKNPENQINGNSMNPSSRTTALNIVADMLRKLNWDKALLCPECEKFRCMCERPASVQPP---PP 314
             .:..::...|..:.|::|.:|||||.|:|||:.   ||     |.....|......|.|   ..
Human   265 -RRGLDDSTGGTPLTPAARISALNIVGDLLRKVG---AL-----ESKLASCRNLVYDQSPNRTGG 320

  Fly   315 PSASEASLFRRAFGG----SSSSVATSSAQSTPTSDCSSAGSLSAGSNIFRRFAERMRNSPDA 373
            |::..:|  :...||    ||:||......|.|::.     .|:.|.|   ..|...|:||.|
Human   321 PASGRSS--KNRDGGERRPSSTSVPLGDKGSVPSNK-----PLAGGEN---PPAPGKRHSPPA 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nudE	NP_001097569.1	GAS	<73..>167	CDD:464001	46/97 (47%)
		NUDE_C	129..>208	CDD:461464	34/83 (41%)
NDE1	XP_006720960.1	SMC_prok_B	<58..>218	CDD:274008	68/159 (43%)
		NUDE_C	166..341	CDD:461464	67/215 (31%)