Protein Alignment nudE and ndel1b

DIOPT Version :9

• Sequence 1: NP_001097569.1
• Gene: nudE / 39169
• FlyBaseID: FBgn0036059
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_958464.1
• Gene: ndel1b / 333957
• ZFINID: ZDB-GENE-030131-5889
• Length: 344
• Species: Danio rerio
• Alignment Length: 391
• Identity: 130/391 - (33%)
• Similarity: 197/391 - (50%)
• Gaps: 67/391 - (17%)

  Fly     2 ESPPMFNSVEDECRYWKERSKQYHKEWTDVKQEYDEFVEQSREMEIEMDATLDQKQSIIKDLTAK 66
            |..|.|:|.::|..|||..|.:|.|...|.::|..||.|.|||:|.|::|.|.|.:..|:||.::
Zfish     4 EMMPKFSSKDEEIDYWKCLSLKYKKSCHDAQEELQEFQEGSRELEAELEAQLGQAEHRIRDLQSE 68

  Fly    67 LTMFERENESLKLKLESHGIDMSNMEKQLETVKKD-------RDTMKVYLRQLEQKNDDLERAHR 124
            ....:.|.:.||.|||.   ..:...||:..::.|       ::.:..|:|:|||.|||||||.|
Zfish    69 NQRLKSEVDILKEKLEQ---QYAQSYKQISMLEDDLLQTRGIKEQLHKYVRELEQANDDLERAKR 130

  Fly   125 ILNESIENFEKMLDQAYEKNALLELEVDEKGLLQEKLQRLMDETRDLKQELNVKSRFTPV--VNG 187
            ....|:|:||:.|:||.|:||.||.|:|||..|...:|||.||.|||:|||.|:.|.:.|  ::.
Zfish   131 ATITSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERTSDVTRMSA 195

  Fly   188 TSVPTANDTNTVNSSMNSSASLPNGIVANGELVKHDNAVATRATSVSVNALNGSLVNRNEYNQQH 252
            .|.||. |.:..:|::.:|.|||...|  |:.::|. .:.|:|.:      ||.
Zfish   196 PSSPTL-DIDKTDSAVQASLSLPATPV--GKTMEHP-FIGTKALT------NGC----------- 239

  Fly   253 SLKNPENQINGNSMNPSSRTTALNIVADMLRKLNWDKALLCPECEKFRCMCERPASVQPPPPPSA 317
                    .||:.:.||:|.:|||||.|:|||:...::.|. .|..|                :.
Zfish   240 --------GNGSPLTPSARISALNIVGDLLRKVGALESKLA-ACRNF----------------AK 279

  Fly   318 SEASLFRRAF----GGSSSSVATSSAQSTPTS--DCSSAGSLSAGSNIFRRFAERMRNSPDASLP 376
            .:|:  |:.:    |...:|.||..:.|..|:  |.::...|..|: :....|.....||...||
Zfish   280 DQAA--RKNYTTGNGNLINSNATKFSHSLHTTYFDKTTMNGLDPGA-LSAAIASPRAVSPPGLLP 341

  Fly   377 L 377
            |
Zfish   342 L 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nudE	NP_001097569.1	NUDE_C	129..>177	CDD:282704	28/47 (60%)
ndel1b	NP_958464.1	iSH2_PI3K_IA_R	<37..>136	CDD:304922	36/101 (36%)
		PRKG1_interact	91..177	CDD:292521	39/85 (46%)
		NUDE_C	135..308	CDD:282704	71/220 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596579
Domainoid	1	1.000	83	1.000	Domainoid score	I8283
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H32567
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4425
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1082224at2759
OrthoFinder	1	1.000	-	-		FOG0002325
OrthoInspector	1	1.000	-	-		otm25440
orthoMCL	1	0.900	-	-		OOG6_104683
Panther	1	1.100	-	-	O	PTHR10921
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4927
SonicParanoid	1	1.000	-	-		X1753
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.930