DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6707 and Pip4p1

DIOPT Version :9

Sequence 1:	NP_648372.1	Gene:	CG6707 / 39168	FlyBaseID:	FBgn0036058	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_001028443.1	Gene:	Pip4p1 / 219024	MGIID:	2448501	Length:	284	Species:	Mus musculus

Alignment Length:	277	Identity:	125/277 - (45%)
Similarity:	164/277 - (59%)	Gaps:	20/277 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ADPERQSLINK--DDGNGYNSVDAVDEGADNPGSNSSVATNEDGNGA----------PTAVPCIG 54
            ||.||..|:::  |.|.|.|.:......|..||...:.:....|.|.          |...|.:.
Mouse     3 ADGERSPLLSEAGDGGAGGNGLAGPGGSATGPGGGLTPSAPPYGAGKHAPPQAFPPFPEGHPAVL 67

  Fly    55 PDELPPPYQ--QSTNTGGVPMVTCRVCQHMIDITTKREQHVVKCTHCNEATPIRNAPAGKKYVRC 117
            |.|.||||.  .|.::|..||:||||||..|::..|..||||||..|||||||:|||.|||||||
Mouse    68 PGEDPPPYSPLTSPDSGSAPMITCRVCQSPINVEGKMHQHVVKCGVCNEATPIKNAPPGKKYVRC 132

  Fly   118 PCNCLLICKSSSQRIACPRPNCKRIINLA---PSPVTPPVPTMPGMCRVTCGHCSDTFLFNTY-H 178
            |||||||||.:|||||||||.|||||||.   |.|::|. |...|: ||.||||.:|||:..: .
Mouse   133 PCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPLSPE-PQPMGV-RVICGHCKNTFLWTEFTD 195

  Fly   179 NALARCPHCRKVSSVGSRFANSRAVMFAIVALVFLITGIAVTIGTYSIASDHGGMYFLYVALFVI 243
            ..||||||||||||:|.|:...|.:...::.|:..:|...:..||:..|..:||:|..:..:.::
Mouse   196 RTLARCPHCRKVSSIGRRYPRKRCICCFLLGLLLAVTATGLAFGTWKHAQQYGGIYAAWAFVILL 260

  Fly   244 SGCMLARSAYYFRLKVS 260
            :...|.|:.|:..:|||
Mouse   261 AVLCLGRALYWACMKVS 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6707	NP_648372.1	Tmemb_55A	3..260	CDD:286827	122/274 (45%)
Pip4p1	NP_001028443.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..82		23/78 (29%)
		Tmemb_55A	4..277	CDD:286827	122/274 (45%)
		CX5R motif	140..146		3/5 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850668
Domainoid	1	1.000	231	1.000	Domainoid score	I2425
eggNOG	1	0.900	-	-		E1_KOG4684
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10279
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3410
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48644
OrthoDB	1	1.010	-	-		D1346704at2759
OrthoFinder	1	1.000	-	-		FOG0002563
OrthoInspector	1	1.000	-	-		otm43856
orthoMCL	1	0.900	-	-		OOG6_106114
Panther	1	1.100	-	-	LDO	PTHR21014
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5639
SonicParanoid	1	1.000	-	-		X1921
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800