Protein Alignment Hez and LSM12

DIOPT Version :10

• Sequence 1: NP_648371.1
• Gene: Hez / 39167
• FlyBaseID: FBgn0036057
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_001356413.1
• Gene: LSM12 / 124801
• HGNCID: 26407
• Length: 230
• Species: Homo sapiens
• Alignment Length: 158
• Identity: 50/158 - (31%)
• Similarity: 78/158 - (49%)
• Gaps: 17/158 - (10%)

  Fly     8 FTVGSIVRCKTCFGDNISGEVVAFDLGVKMLIMKCPSSNGGGDEQTTCNVTIVNLSLCMDIEIVK 72
            |:|||.|.|:||....:.|||||||...|||.:|||||:|   :....::.::||....::||:.
Human     9 FSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSG---KPNHADILLINLQYVSEVEIIN 70

  Fly    73 EAIPPAEVQQPEP---IDLPMIRERYRYATEHRTLSCRSYHPNASPFGQALFRLLVKRFGDPAII 134
            :     ..:.|.|   :::..:..:.|...|.:.....:.....|..||.||:.:.|...|  ..
Human    71 D-----RTETPPPLASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKD--CK 128

  Fly   135 WQNKGDQVAINILRQVVIDAPYATENIR 162
            ||.|.    |.::.:|||..||..||.:
Human   129 WQEKN----IVVMEEVVITPPYQVENCK 152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hez	NP_648371.1	LSm12_N	6..69	CDD:212482	26/60 (43%)
		AD	82..177	CDD:214962	22/84 (26%)
LSM12	NP_001356413.1	Required for NAADP and TPCN2 binding. /evidence=ECO:0000269|PubMed:34362892	4..67		26/60 (43%)
		LSm12_N	7..67	CDD:212482	26/60 (43%)
		AD	78..165	CDD:214962	21/81 (26%)