| Sequence 1: | NP_001246706.1 | Gene: | CalpB / 39165 | FlyBaseID: | FBgn0025866 | Length: | 925 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001739.3 | Gene: | CAPN2 / 824 | HGNCID: | 1479 | Length: | 700 | Species: | Homo sapiens |
| Alignment Length: | 736 | Identity: | 326/736 - (44%) |
|---|---|---|---|
| Similarity: | 456/736 - (61%) | Gaps: | 89/736 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 230 GRKATSARQNSVSKG-------------DFQSLRDSCLANGTMFEDPDFPATNASL------MYS 275
Fly 276 RRPDRYYEWLRPGDIADDPQFFVEGYSRFDVQQGELGDCWLLAAAANLTQDSTLFFRVIPPDQDF 340
Fly 341 QENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTEKNEFWSALLEKAYAKLHGSYEALK 405
Fly 406 GGTTCEAMEDFTGGVTEWYDIKEAPPNLFSIMMKAAERGSMMGCSLE----PDPHVLEAETPQGL 466
Fly 467 IRGHAYSITKVCLMDISTPNRQGKL-PMIRMRNPWGNDAEWSGPWSDSSPEWRFIPEHTKEEIGL 530
Fly 531 NFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQHSSRRKWEMSMFEGEWTSGVTAGGCRNF 595
Fly 596 LETFWHNPQYIISLEDPDDEDDDGK--CTAIVALMQKNRRSKRNVGIDCLTIGFAIYHLTDRDMQ 658
Fly 659 VKPQGL----------NFFKYRASVARSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFII 713
Fly 714 RVFSETRNNMEENDDEV-----GFGETDDRIAPSLPPPTPKEEDDPQRIALRRLFDSVAGSDEEV 773
Fly 774 DWQELKRILDHSMRDVM-----VGSDGFSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRA 833
Fly 834 VFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGSREGQIPFDDFLMCAIKVRTFIE 898
Fly 899 MFRERDTDNSDTAFFNLDDWL 919 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CalpB | NP_001246706.1 | PD-C2-AF1 | 33..225 | CDD:286403 | |
| Drf_FH1 | 37..189 | CDD:283903 | |||
| Peptidase_C2 | 260..556 | CDD:279042 | 163/306 (53%) | ||
| Calpain_III | 574..721 | CDD:279416 | 77/158 (49%) | ||
| EF-hand_7 | 759..825 | CDD:290234 | 31/70 (44%) | ||
| EFh | 761..826 | CDD:298682 | 31/69 (45%) | ||
| FRQ1 | 827..>908 | CDD:227455 | 20/80 (25%) | ||
| CAPN2 | NP_001739.3 | Peptidase_C2 | 46..342 | CDD:306994 | 163/306 (53%) |
| Domain III | 345..514 | 83/180 (46%) | |||
| Calpain_III | 363..507 | CDD:307285 | 76/151 (50%) | ||
| Linker | 515..529 | 2/13 (15%) | |||
| Domain IV | 530..700 | 61/186 (33%) | |||
| EFh_PEF_CAPN2 | 533..700 | CDD:320074 | 58/167 (35%) | ||
| EF-hand motif | 533..561 | CDD:320074 | 13/31 (42%) | ||
| EF-hand motif | 576..605 | CDD:320074 | 14/28 (50%) | ||
| EF-hand motif | 606..636 | CDD:320074 | 8/29 (28%) | ||
| EF-hand motif | 642..670 | CDD:320074 | 7/27 (26%) | ||
| EF-hand motif | 672..700 | CDD:320074 | 7/24 (29%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 356 | 1.000 | Domainoid score | I986 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0045 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 643 | 1.000 | Inparanoid score | I809 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S2747 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D704215at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000071 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm8590 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100404 | |
| Panther | 1 | 1.100 | - | - | O | PTHR10183 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X74 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.820 | |||||