DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CalpB and CG17765

DIOPT Version :9

Sequence 1:	NP_001246706.1	Gene:	CalpB / 39165	FlyBaseID:	FBgn0025866	Length:	925	Species:	Drosophila melanogaster
Sequence 2:	NP_610592.1	Gene:	CG17765 / 36111	FlyBaseID:	FBgn0033529	Length:	199	Species:	Drosophila melanogaster

Alignment Length:	181	Identity:	53/181 - (29%)
Similarity:	84/181 - (46%)	Gaps:	13/181 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   744 PPPTPKEEDDPQRIALRRLFDSVAGSDE--EVDWQELKRILDHSMRDVMVGSDGFSKDAVRSMVA 806
            |||......:.|.....:.:.|:...|.  :::..||:..|      |....|.||.:|.:.|::
  Fly    19 PPPGAFPPQNAQVSPQAQQWFSMVDRDRSGKINASELQAAL------VNGRGDHFSDNACKLMIS 77

  Fly   807 MLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALA 871
            |.|.|.||.:...|||.|...|.:|..|||.||...:|.|:...|..|....|:..:...:|.|.
  Fly    78 MFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFINFLV 142

  Fly   872 HR---YGSREGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWL 919
            .:   .|.:|  :..|.|::..::|:.|.|.||:|||..:.|.....:|:|
  Fly   143 KKSDPQGHKE--VSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIGFEDFL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpB	NP_001246706.1	PD-C2-AF1	33..225	CDD:286403
		Drf_FH1	37..189	CDD:283903
		Peptidase_C2	260..556	CDD:279042
		Calpain_III	574..721	CDD:279416
		EF-hand_7	759..825	CDD:290234	19/67 (28%)
		EFh	761..826	CDD:298682	20/66 (30%)
		FRQ1	827..>908	CDD:227455	26/83 (31%)
CG17765	NP_610592.1	FRQ1	26..162	CDD:227455	39/143 (27%)
		EFh	39..92	CDD:238008	16/58 (28%)
		EFh	105..159	CDD:298682	15/55 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448315
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840