Protein Alignment CalpB and clp-10

DIOPT Version :9

• Sequence 1: NP_001246706.1
• Gene: CalpB / 39165
• FlyBaseID: FBgn0025866
• Length: 925
• Species: Drosophila melanogaster
• Sequence 2: NP_001367887.1
• Gene: clp-10 / 189220
• WormBaseID: WBGene00021041
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 137/520 - (26%)
• Similarity: 191/520 - (36%)
• Gaps: 130/520 - (25%)

  Fly   333 VIPPDQDFQENYA--GIFHFKFWQYGKWVEVVIDDRLPTY-NGELIYMHSTEKNEFWSALLEKAY 394
            :||..|     |:  |::..|....|||..:::||..|.| |...|.:....:|:.|..|:|||.
 Worm    14 IIPKKQ-----YSKHGVYQVKVCVEGKWEVIIVDDFFPCYRNTNSIAIAVGRRNQLWVPLIEKAM 73

  Fly   395 AKLHGSYEALKGGTTCEAMEDFTGGVTEWY------DIKEAPPNLFSIMMKAAERGSMMGCSLEP 453
            ||:.|||..|.|.:....:...||.....|      .|.|.....::.::.:.|.|.:..|...|
 Worm    74 AKVLGSYSKLHGASLARGLSMLTGASCVRYKCPQTLKIDEEVDTFWAQLVSSQESGFLTCCHCGP 138

  Fly   454 -DPHVLEAE-TPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPWGNDAEWSGPWSDSSPE 516
             :....||| ...||:..|||||..|.       :.||. .::|:|||||... |:|.|||...|
 Worm   139 FESEEAEAEFKALGLVTSHAYSILDVV-------HEQGH-RLLRIRNPWGQFV-WNGKWSDGWLE 194

  Fly   517 WRFIPEHTKEE-IGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQHSSRRKWEMSMFE 580
            |   |...|.. :....|..|.|||..|||:..|..|.:|.|..|
 Worm   195 W---PIDMKRALLDKRSDETGAFWMDLQDFVKRFASVTVCKLRMD-------------------- 236

  Fly   581 GEWTSGVTAGGCRNFLETFWHNP---QYIISLEDPDDEDDDGKCTAIVALMQKNRRSKRNVGIDC 642
              |:.      .|...|...|..   |.:|:         :..|...|...||...||.    |.
 Worm   237 --WSE------LRATQEVGRHADSALQIVIT---------EQLCEVSVTAFQKGSFSKE----DN 280

  Fly   643 LTIGFAIYHLTDRDMQVKPQGLNFFKYRASVARSPHFINTREVCARFKLPPGHYLIV---PSTFD 704
            ||......|....|.::.    ...|....:|.: ||     ....|.||.|.|.:|   |.:..
 Worm   281 LTDLMVCVHKISEDGRIG----ELIKMSYEIADN-HF-----TIDEFFLPRGVYQVVCHSPHSLV 335

  Fly   705 PNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIAPSLPPPTPK-----------EEDDPQRIA 758
            .|..|  ::.:...||..:        |||:        .|.:|.           ||...|.|.
 Worm   336 TNTTG--VVNIIVHTRFPI--------FGES--------VPMSPLTRLESLHRVIIEEGVVQNIK 382

  Fly   759 L-----RRLFDSVAGSDEEVD-WQELKRI---LDHSMRDVMVGSDG--FSKDAV----RSMVAML 808
            |     |.|.....||...|| :.|.|.:   :|:|....:..|.|  ...|.|    |.::|:|
 Worm   383 LDGVVIRTLNQKFRGSITMVDNYMEQKYLHVKVDNSKSMNVQSSRGSLLIADVVPPRSRQVIAVL 447

  Fly   809  808
             Worm   448  447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpB	NP_001246706.1	PD-C2-AF1	33..225	CDD:286403
		Drf_FH1	37..189	CDD:283903
		Peptidase_C2	260..556	CDD:279042	75/234 (32%)
		Calpain_III	574..721	CDD:279416	31/152 (20%)
		EF-hand_7	759..825	CDD:290234	18/65 (28%)
		EFh	761..826	CDD:298682	16/58 (28%)
		FRQ1	827..>908	CDD:227455
clp-10	NP_001367887.1	CysPc	<1..241	CDD:412132	79/271 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820