DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CalpB and clpr-3

DIOPT Version :9

Sequence 1:	NP_001246706.1	Gene:	CalpB / 39165	FlyBaseID:	FBgn0025866	Length:	925	Species:	Drosophila melanogaster
Sequence 2:	NP_492904.2	Gene:	clpr-3 / 186784	WormBaseID:	WBGene00010417	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	261	Identity:	57/261 - (21%)
Similarity:	100/261 - (38%)	Gaps:	58/261 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 FFRVIPPDQDFQ------ENYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTEKNEF--- 385
            |.|:...|..|.      |.:|.:  .|....|:|..:..|..||        |:.....|:
Worm    15 FIRLSSKDDVFAISDKECEKHAKL--LKLLADGEWKIIKTDFHLP--------MNKQSIEEYAWM 69

  Fly   386 -----WSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKEAPPNLFSI--MMKAAER 443
                 |:|.:||.:|||.|||::|.......|....||..::.|:::.. .|..::  |:..|..
Worm    70 IGKQTWAAFIEKGFAKLFGSYKSLSAKPIDVAFRKLTGAFSKNYELRSF-KNCDAVWDMIVEAHL 133

  Fly   444 GSMMGCSLEPDPHVLEAETPQ------GLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPWGN 502
            ...:.|:.:..   |:.|:.:      |:.:.|||:|    |..:...|.:    ::::.|....
Worm   134 AGFLLCTSKLS---LDEESAEYIFNSTGIKQNHAYAI----LNSVVFENHR----LVQIGNTHAC 187

  Fly   503 DAEWSGPWSDSSPEW--------RFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSP 559
            |     .|.:...||        :|..:..:.....:.| |..|||....:..||..:.:|....
Worm   188 D-----KWKELHKEWNSLHYFYNKFSSKLPRRPYISHLD-DMSFWMDIDQYCEHFSSLTVCEYRK 246

  Fly   560 D 560
            |
Worm   247 D 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpB	NP_001246706.1	PD-C2-AF1	33..225	CDD:286403
		Drf_FH1	37..189	CDD:283903
		Peptidase_C2	260..556	CDD:279042	55/255 (22%)
		Calpain_III	574..721	CDD:279416
		EF-hand_7	759..825	CDD:290234
		EFh	761..826	CDD:298682
		FRQ1	827..>908	CDD:227455
clpr-3	NP_492904.2	CysPc	<40..242	CDD:381776	49/227 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158990
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740