Protein Alignment CalpB and LOC1280602

DIOPT Version :10

• Sequence 1: NP_524016.4
• Gene: CalpB / 39165
• FlyBaseID: FBgn0025866
• Length: 925
• Species: Drosophila melanogaster
• Sequence 2: XP_320457.4
• Gene: LOC1280602 / 1280602
• VectorBaseID: AGAMI1_000303
• Length: 869
• Species: Anopheles gambiae
• Alignment Length: 787
• Identity: 402/787 - (51%)
• Similarity: 499/787 - (63%)
• Gaps: 110/787 - (13%)

  Fly   245 DFQSLRDSCLANGTMFEDPDFPATNASLMYSRRPDR--YYEWLRPGDIADDPQFFVEGYSRFDVQ 307
            |:..||..||..|.:||||:|||.::||.:|....|  .|:||||.:|:.|..|.|:|:||||:|
Mosquito    87 DYYKLRTDCLRAGKLFEDPEFPADDSSLHFSSFAGRQSQYKWLRPHEISPDAVFDVDGFSRFDIQ 151

  Fly   308 QGELGDCWLLAAAANLTQDSTLFFRVIPPDQDFQE------NYAGIFHFKFWQYGKWVEVVIDDR 366
            ||.||||||||||||||....||.||:|.|.|..:      :|||||||:||::|:|.:||:|||
Mosquito   152 QGLLGDCWLLAAAANLTTFPVLFSRVVPDDNDRIQGGRKGVDYAGIFHFRFWRFGQWYDVVVDDR 216

  Fly   367 LPTYNGELIYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKEAPP 431
            |||..|:|:|:.|:.|:||||||||||||||.||||||.||:..|||||||||:||.|::|:||.
Mosquito   217 LPTIRGQLVYIKSSTKHEFWSALLEKAYAKLFGSYEALSGGSASEAMEDFTGGLTEGYEMKDAPE 281

  Fly   432 NLFSIMMKAAERGSMMGCSLEPDPHVLEAETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRM 496
            .||.::.|.....:|..||:|.....:|..|||||::||||||||...:||.||..:||:.::|:
Mosquito   282 GLFEMIEKGCNNYAMFACSIEAGAGEMEQVTPQGLVKGHAYSITKAQAVDIETPRVKGKIQLLRL 346

  Fly   497 RNPWGNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDS 561
            ||||||:.||:|.|||.|||||||.|.||..|||.|:.||||||||.||...|||||:|:||||.
Mosquito   347 RNPWGNENEWNGAWSDKSPEWRFINEDTKRSIGLTFEVDGEFWMSFPDFRKCFDRVEMCHLSPDC 411

  Fly   562 LTEDQQHSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDEDDDGKCTAIVA 626
            ....|:  ||..|....|||||..|.|||||||:.:||||||||:|.|:|||.:|:...||.||:
Mosquito   412 PIALQE--SRFAWRQCAFEGEWVLGSTAGGCRNYPDTFWHNPQYVIRLDDPDADDEAKLCTLIVS 474

  Fly   627 LMQKNRRSKRNVGIDCLTIGFAIYHLTDRDMQVKPQGLNFFKYRASVARSPHFINTREVCARFKL 691
            |:|||||||||.||.|||||||||.:...|:|.||....||....|.|:|. |||.|||..||:|
Mosquito   475 LIQKNRRSKRNKGITCLTIGFAIYRVEPSDLQRKPLPREFFTSHLSAAKST-FINLREVTCRFRL 538

  Fly   692 PPGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIAPSLP--------PPTP 748
            |||.|:|:||||:|||||||:||||||...||:|||..:|.|...|. :||.|        .|:|
Mosquito   539 PPGSYVIIPSTFEPNEEGEFMIRVFSECAANMQENDSAIGVGTPTDP-SPSKPSAGVGPPSKPSP 602

  Fly   749 KEED----DPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMV------------------ 791
            |:.|    |.||..:.|||..|||.|.||||.|||.:||...|:.:|
Mosquito   603 KDVDTGVTDAQRATMERLFIEVAGEDGEVDWMELKLVLDRCFREDIVKASRGISRTYQSTRTTPL 667

  Fly   792 --------------------------------------GSD------------------------ 794
                                                  |.|
Mosquito   668 EKQQSVAGTASAAISQTSLERSLCGMWSTLQNLFRDIAGGDNSPPAAANGERRELMRSENVTQVH 732

  Fly   795 ------GFSKDAVRSMVAMLDKDRSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRG 853
                  ||||||.||||||||:|.||:||..||:.||.|||:|:.|||.|||.::|.|..|.||.
Mosquito   733 ADPSNPGFSKDACRSMVAMLDEDGSGKLGLAEFQKLLADIARWKGVFKQYDTDQSGRISPFELRA 797

  Fly   854 ALNSAGYHLNNRLLNALAHRYGSREGQIPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDW 918
            ||.||||.|||.::|.|.|||||:||:|.||||:.||:|:||..::|:.||..|.:.|.|.|::|
Mosquito   798 ALQSAGYTLNNHIINMLMHRYGSKEGEIWFDDFITCAVKIRTMFDIFKARDLSNRNEARFTLEEW 862

  Fly   919 LERTIYS 925
            :.:||||
Mosquito   863 ITKTIYS 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CalpB	NP_524016.4	PHA03247	<40..207	CDD:223021
		Peptidase_C2	260..556	CDD:459889	179/303 (59%)
		Calpain_III	579..716	CDD:460050	88/136 (65%)
		EFh_PEF_CalpA_B	758..925	CDD:320071	96/252 (38%)
		EF-hand motif	758..786	CDD:320071	16/27 (59%)
		EF-hand motif	799..829	CDD:320071	20/29 (69%)
		EF-hand motif	830..860	CDD:320071	16/29 (55%)
		EF-hand motif	866..894	CDD:320071	17/27 (63%)
		EF-hand motif	895..925	CDD:320071	11/29 (38%)
LOC1280602	XP_320457.4	None