DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CalpB and LOC101731595

DIOPT Version :9

Sequence 1:	NP_001246706.1	Gene:	CalpB / 39165	FlyBaseID:	FBgn0025866	Length:	925	Species:	Drosophila melanogaster
Sequence 2:	XP_031758228.1	Gene:	LOC101731595 / 101731595	-ID:	-	Length:	474	Species:	Xenopus tropicalis

Alignment Length:	488	Identity:	190/488 - (38%)
Similarity:	273/488 - (55%)	Gaps:	53/488 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 DFQSLRDSCLANGTMFEDPDFPATNASLMYSR-RPD----RYYEWLRPGDIADDPQFFVEGYSRF 304
            |::.||...|.....|||.:|||:.|||..:: .|:    :...||||.:|..:|:|...|.:||
Frog    18 DYEQLRAQSLPPNPPFEDKEFPASQASLGSNKLGPESNTAKGIVWLRPSEIHPNPEFITSGATRF 82

  Fly   305 DVQQGELGDCWLLAAAANLTQDSTLFFRVIPPDQDFQENYAGIFHFKFWQYGKWVEVVIDDRLPT 369
            |:.|.:|||||:|::.|.||.:......|:|.||.|:.||||||||:|||.|.|.:||:||:|||
Frog    83 DICQQDLGDCWILSSMACLTLNEEYLSLVVPQDQSFKNNYAGIFHFRFWQRGDWTDVVVDDKLPT 147

  Fly   370 YNGELIYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKEAPPNLF 434
            .:.:|:::.|.::||||:||||||:|||:|||||:.|.....||||.||||.|.|.:|.||.:||
Frog   148 TDKKLVFVKSAQENEFWAALLEKAFAKLYGSYEAIWGKNPILAMEDLTGGVCESYSLKSAPGDLF 212

  Fly   435 SIMMKAAERGSMMGCSLEPDPHVLEAETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNP 499
            ..:.::.....::.||.:...   |......::.||:||||..    ...|..:||:.:||:|||
Frog   213 QTIQRSVRTQCLLTCSTDKKK---EGTEESSIVAGHSYSITGA----EEVPYGKGKVQLIRLRNP 270

  Fly   500 WGNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDS-LT 563
            ||: |||.|.|.|..|||..:....|:.: ||...||||||.:.|.:..::.||||.::..| :.
Frog   271 WGS-AEWKGAWRDDGPEWNDVTPEVKKAL-LNKMEDGEFWMPYADVVKEYNTVEICYVASSSGVN 333

  Fly   564 EDQQHSSRRKWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDED----DDGKCTAI 624
            ..:.|     |.::...|.|..|       |..|||..:|::...||.||::.    |...||.|
Frog   334 MKEPH-----WSLTQTGGSWNKG-------NPAETFLADPRFRFKLEVPDEDQAAAGDAALCTVI 386

  Fly   625 VALMQKNRRSKRNVGIDCLTIGFAIYHL-TDRDMQVKPQGLNFFK----YRASVARSPHFINTRE 684
            ||||||. ..|.|:      :.|.:|.| .:...||..:.|...|    .:.:..::.|
Frog   387 VALMQKT-VPKDNI------LDFQLYELPKEVSAQVLVKDLKSIKDINANQRNSGKTKH------ 438

  Fly   685 VCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFS 717
                |::|.|.|||||...|||::.:|.|||||
Frog   439 ----FRVPKGEYLIVPKPSDPNQDIDFCIRVFS 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpB	NP_001246706.1	PD-C2-AF1	33..225	CDD:286403
		Drf_FH1	37..189	CDD:283903
		Peptidase_C2	260..556	CDD:279042	133/300 (44%)
		Calpain_III	574..721	CDD:279416	50/153 (33%)
		EF-hand_7	759..825	CDD:290234
		EFh	761..826	CDD:298682
		FRQ1	827..>908	CDD:227455
LOC101731595	XP_031758228.1	Peptidase_C2	33..325	CDD:395523	133/300 (44%)
LOC101731595	XP_031758228.1	Calpain_III	337..470	CDD:412194	51/160 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704215at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010