DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CalpB and pef1

DIOPT Version :9

Sequence 1:	NP_001246706.1	Gene:	CalpB / 39165	FlyBaseID:	FBgn0025866	Length:	925	Species:	Drosophila melanogaster
Sequence 2:	XP_002938526.1	Gene:	pef1 / 100144965	XenbaseID:	XB-GENE-1013238	Length:	283	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	62/243 - (25%)
Similarity:	98/243 - (40%)	Gaps:	57/243 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   692 PPGHYLIVPST-FDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIAPSLPPPTPKEEDDPQ 755
            |.|.|.:..|| :...:.|.:                   |.|.....|.|.:         ||:
Frog    81 PGGPYSVPGSTPYGNQQHGPY-------------------GQGAPTGNIPPGV---------DPE 117

  Fly   756 RIALRRLFDSVAGSDEEVDWQELKRILDHS-------MRDVMVGSD--GFSKDAVRSMVAMLDKD 811
            ..:..:..||                 |||       ::..:|.|:  .|:.:....|:.|.||.
Frog   118 AFSWFQTVDS-----------------DHSGYISLKELKQALVNSNWSSFNDETCMMMMNMFDKS 165

  Fly   812 RSGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAHRYGS 876
            .|||:....|.||...|.:||.:|:.||..|:|||:...|..||...||.|:.:.:..:..||..
Frog   166 NSGRIDLFGFSALWRFIQQWRNLFQQYDRDRSGSINQGELHQALCQMGYQLSPQFVQLVMSRYAQ 230

  Fly   877 REGQ--IPFDDFLMCAIKVRTFIEMFRERDTDNSDTAFFNLDDWLERT 922
            |..|  :..|.|:....::::..:.|||:||..|..|..:.:|:|..|
Frog   231 RSVQPGLQLDRFIQICTQLQSMTQAFREKDTGLSGNAKLSYEDFLTMT 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CalpB	NP_001246706.1	PD-C2-AF1	33..225	CDD:286403
		Drf_FH1	37..189	CDD:283903
		Peptidase_C2	260..556	CDD:279042
		Calpain_III	574..721	CDD:279416	6/29 (21%)
		EF-hand_7	759..825	CDD:290234	17/74 (23%)
		EFh	761..826	CDD:298682	18/73 (25%)
		FRQ1	827..>908	CDD:227455	27/82 (33%)
pef1	XP_002938526.1	EFh_PEF_peflin	117..282	CDD:320059	50/179 (28%)
		EF-hand motif	117..146	CDD:320059	6/45 (13%)
		EF-hand motif	154..183	CDD:320059	10/28 (36%)
		EF-hand motif	184..214	CDD:320059	12/29 (41%)
		EF-hand motif	220..250	CDD:320059	6/29 (21%)
		EF-hand motif	251..282	CDD:320059	10/28 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910