Protein Alignment Taf2 and TAF2

DIOPT Version :9

• Sequence 1: NP_001261668.1
• Gene: Taf2 / 39164
• FlyBaseID: FBgn0011836
• Length: 1221
• Species: Drosophila melanogaster
• Sequence 2: NP_009971.1
• Gene: TAF2 / 850409
• SGDID: S000000638
• Length: 1407
• Species: Saccharomyces cerevisiae
• Alignment Length: 1502
• Identity: 320/1502 - (21%)
• Similarity: 538/1502 - (35%)
• Gaps: 484/1502 - (32%)

  Fly     9 EVPLRPFKLAHQVVSLTGISFERRSIIGVVELTIVPNSENLRLIRLNAKQLRIYSVVLNDVCQAD 73
            |:..|.|::||:.:|| .|......|.|...:.|:|..:||..:..:.|::.|..|::.:.....
Yeast    22 EMKFRNFRVAHEKISL-DIDLATHCITGSATIIIIPLIQNLEYVTFDCKEMTIKDVLVENRRCDQ 85

  Fly    74 FTYFDPF---------QNICYKEHKSRALEVYSKHHLTAAQYTDPDVNNGELLIQVPPEGYSMIQ 129
            |.:.||.         ||:.|.::.............:..:|.:.| :..:|.|::|......::
Yeast    86 FIHDDPLQTNLNGLTSQNVLYSDNSIEQSHFLRSKFASLNEYPETD-SKSQLTIKIPSSIKISLE 149

  Fly   130 EGQGL------------------------RIRIEFSLENPKCGVHFVIPPASTDEETQMNSSHMF 170
            :...|                        .::||:.:.|||.|:.|         :|........
Yeast   150 DANALSNYTPITPSIKTTPGFQESVFTPITLQIEYEIRNPKSGIKF---------DTVYADKPWL 205

  Fly   171 TNCYE------NSSRLWFPCVDSFADPCTWRLEFTV----------------------------- 200
            .|.|.      :|:..|.||||...:..||.|||:|
Yeast   206 WNVYTSNGEICSSASYWVPCVDLLDEKSTWELEFSVPRLVKNIGTSKLIGQNGEESEKEKEDTPE 270

  Fly   201 ------------------DKNM------------------------------------------- 204
                              |.|:
Yeast   271 HDEEEEGKPARVIKDEDKDSNLKNDEEGKNSKSKDAQDNDEEEEEGESDEEEEEGEEERRNIEES 335

  Fly   205 -------TAVSCGELLEVIMTP---DLRKKTFHYSVSTPVCAPNIALAVGQF------------- 246
                   ..|.|.|...:...|   ||.||...:.:..||...:|..|:|.|
Yeast   336 NNPSLRDVIVCCSEYSNIKELPHPIDLTKKKCIFQIINPVAPHHIGWAIGAFNSWSLPLISPPSV 400

  Fly   247 ----EIYVDPHMHEVTH-------------------FCLP----GLLPLLKNTVRYLHEAFEFYE 284
                |:..|.....|..                   |.||    ..|.::.:|| ...:..:||.
Yeast   401 DAEDEVEEDKLRENVVDNVNDTMDDDIGSDIIPIQIFTLPTQETDELTVINSTV-VCQKIIDFYS 464

  Fly   285 ETLSTRYPFSCYKQVFVDELDTDISAYATMSIASVNLLHSIAIIDQTYISRTFMSRAVAEQFFGC 349
            :...: |||:||..||:....:....:|.:.|.:..||:.:.:||:.:.:...::.|:|.|:...
Yeast   465 KEFGS-YPFTCYSMVFLPTAPSKHMDFAALGICNTRLLYPLEVIDKAFSTTNELAWALANQWSCV 528

  Fly   350 FITSHHWSDTWLAKGIAEYLCGLYSRKCFGNNEYRAWVQSELARVVRYEEQYGGIILDCSQPPAP 414
            .||....:|.|...|||.|:....::|..|||.|:..::.....:|   ||      |..:||..
Yeast   529 NITPLDMNDYWCCLGIAGYMVFQVTKKLMGNNTYKYQLKRNSEAIV---EQ------DFEKPPIG 584

  Fly   415 LPVSGTNQSAASSKQQEIVHYFPIKSLHTVSPKYVEAMRRKAHFVIRMLENRIGQ--------EL 471
            ...:|:::              ||    :.|.|.:..::.||..::.:|:.|:.:        .:
Yeast   585 STFTGSSR--------------PI----SWSSKDLSFIQLKAPMILHILDRRMTKTERSFGMSRV 631

  Fly   472 LIQVFNKQLA--LASSAATTKIGAGLWSQLLISTNIFIKAIFTVTGKDMSVFMDQWVRTGGHAKF 534
            |.::|.:.::  |.:::.|              ::.|......|....:..|.::||...|....
Yeast   632 LPKIFLQAMSGDLPNNSLT--------------SSHFQHVCERVNKSKLENFFNEWVYGSGVPIL 682

  Fly   535 SLTSVFNRKRNTIELEIRQ---------DYVNQRGIRK----------------YNGPLMVQLQE 574
            .:|..|||||..|||.|||         ..|.:.|..|                :.|.:.:::.|
Yeast   683 RVTQRFNRKRMVIELGIRQVQDEELGHEKVVGEEGFFKSALDHLEHPDLNRTECFTGSMTIRIHE 747

  Fly   575 LDGT-FKHTLQIESTLVKSDITCHSKSRR-----------------NKKKKIPL---CTG----- 613
            .||| ::|.::|:.|..|.||..::|.||                 |::|.|.:   |.|
Yeast   748 HDGTPYEHIVEIKDTFTKIDIQYNTKYRRLRKRGGGANDENGVENNNEEKPIVVDVNCLGNVYMS 812

  Fly   614 -EEVD----MDLSAMDDSPVL--------WIRLDPEMILLRDLIIEQPDFQWQYQLRHERDVTAQ 665
             ||..    .:.:...:|..|        |||:|.::..:..:.|.|||:.:..|||.:.|:.||
Yeast   813 PEECSRFSLTEFNRTSESNELLKQNEAFEWIRIDSDLEWICQMHINQPDYMFSSQLRQDGDIEAQ 877

  Fly   666 FQAIQALQKYPTNATRLALT------DTIESERCFYQVRCEAAHSLTKVANQMVASWSGPPAMLN 724
            .:||:..:....|....:|.      .|...||.|:.:|..|..:|:|.......: .|...::.
Yeast   878 LEAIRYYEDVVVNGGVKSLVYSSILFRTAIDERYFFGIRLAACEALSKYVYDPDFT-GGVKHLIQ 941

  Fly   725 IFRKFFGSFSAPHIIKLNNFSNFQLYFLQKAIPVAMAGLRTSHGICPPEVMRFLFDLFKYNENSR 789
            ||:..| .....:|.|.|||.|.:|||||..||..:|.::..:|.||..|.:||.|:..||||..
Yeast   942 IFQILF-CLEDSNIPKSNNFENPKLYFLQCNIPKYLAKVKNENGKCPKLVKQFLLDILVYNENGE 1005

  Fly   790 NHYTDAYYRAALVEALGETLTPVVSVAIHGTQITTDSLSTDAKLVLDEV-TRLL---NMEKHLPS 850
            |.|:|..|..:|:|       .||.||::         ....|..:::| |:||   |:...|.|
Yeast  1006 NKYSDDAYVRSLIE-------NVVKVALN---------EYKDKAYMEKVKTQLLRYENLVNWLSS 1054

  Fly   851 YKYMVSVSCLKVIRKLQKFGHLPSLPHIYRSYAEYGIYLDLRIAAMECLVDFVKVDGRSEDLEHL 915
            |:.::..:.:....||.|.|          :|                  ||.::.|.   :.|.
Yeast  1055 YESLIKTTIMYAKYKLHKVG----------AY------------------DFTELTGM---IMHT 1088

  Fly   916 ITLLETDPDPAARHALAQLLIDNPPFTRES---------RSRLDKPNLVDRLWFSINRLPYDTKL 971
            :|                |.|:|...:|||         :..|.:..|.::     :.|...|::
Yeast  1089 LT----------------LGINNGDISRESFQNEFLMVLKIMLLEGGLKNK-----DALVLFTEI 1132

  Fly   972 RCDIVDLYYALYGTKRPNCLQAGENQSFYKD-LMKDNNSSVGS-------VTGSFKKTSDS-KSH 1027
            .|                         |::| .::|.:..|.|       :.||....||. ||.
Yeast  1133 LC-------------------------FHEDSYIRDKSVDVLSECVNLVVMDGSLDTISDDIKSS 1172

  Fly  1028 LPTPTNTLDNEPQERQKPAMVTIKRTATEAFEVGDEIIKLER--SEEITVLDE----------PV 1080
            :.:..|.:.|...|......::       ...|.|..||:|:  .:.|:.|.:          |:
Yeast  1173 VQSVHNEVKNIKSEDDIELFLS-------GHYVDDMKIKIEKIGRQNISGLIQICRDMFKGYSPL 1230

  Fly  1081 NVQAYD-SETKVNALQADEEARDTHQAAKRLKNEMYAEDDNSSTMLDVGDSTRY---ESSHEEGK 1141
            .:..:| ....|.:|...::..|       |...||...::....|:.....|.   .:|:||||
Yeast  1231 KILLWDVLNLPVLSLYQRKQIHD-------LVRVMYTLINSFVVRLETPRERRLVAKMNSNEEGK 1288

  Fly  1142 LK---SGDGGLKKKKKKE--------KKKHKHKHKHRHSKD---------KDKDKDKERKDKDKR 1186
            |.   ..:..||...|||        ||.:|.|...:..|.         |.|...|:||.|.
Yeast  1289 LDIVIKRESILKVHIKKEVTSTVEAPKKANKIKISLKGDKPVRKVEKQIVKPKVTSKQRKVKS-- 1351

  Fly  1187 DPHISRL 1193
              |::|:
Yeast  1352 --HVNRM 1356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf2	NP_001261668.1	M1_TAF2	16..544	CDD:189018	133/716 (19%)
TAF2	NP_009971.1	M1_like_TAF2	30..674	CDD:341074	126/697 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346168
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1932
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I710
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004794
OrthoInspector	1	1.000	-	-		oto99976
orthoMCL	1	0.900	-	-		OOG6_102824
Panther	1	1.100	-	-	LDO	PTHR15137
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1471
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.780