Protein Alignment Taf2 and Taf2

DIOPT Version :9

• Sequence 1: NP_001261668.1
• Gene: Taf2 / 39164
• FlyBaseID: FBgn0011836
• Length: 1221
• Species: Drosophila melanogaster
• Sequence 2: XP_011243959.1
• Gene: Taf2 / 319944
• MGIID: 2443028
• Length: 1212
• Species: Mus musculus
• Alignment Length: 1213
• Identity: 558/1213 - (46%)
• Similarity: 771/1213 - (63%)
• Gaps: 104/1213 - (8%)

  Fly    13 RPFKLAHQVVSLTGISFERRSIIGVVELTIVPNSENLRLIRLNAKQLRIYSVVLNDVCQADFTYF 77
            ||:||.||||.:..|:|:|:|::|.|||||.|...||..|:||:||.|||.|.:||: :|.|.|.
Mouse    24 RPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDL-EAAFIYN 87

  Fly    78 DPFQNICYKEHKSRALEVYSKHHLTAAQYTDPDVNNGELLIQVPPEGYSMIQ----EGQGLRIRI 138
            ||...:|:.|.|.|.|..:|..:..|....|||..||||.|:||.|.:..:.    |.:.|:|.|
Mouse    88 DPTLEVCHSESKQRNLNYFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDGKAPELKVLKIHI 152

  Fly   139 EFSLENPKCGVHFVIPPASTDEETQMNSSHMFTNCYENSSRLWFPCVDSFADPCTWRLEFTVDKN 203
            .|||:.||.|:|||:|  |.:.......:|:|:..|:||:|.|||||||:::.|||:||||||..
Mouse   153 NFSLDQPKGGLHFVVP--SVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAA 215

  Fly   204 MTAVSCGELLEVIMTPDLRKKTFHYSVSTPVCAPNIALAVGQFEIYVDPHMHEVTHFCLPGLLPL 268
            |.|||.|:|:|.:.|.|:|||||||.::.|..|.||:||:|.|||.|||:||||||||||.||||
Mouse   216 MVAVSNGDLVETVYTHDMRKKTFHYMLTIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPL 280

  Fly   269 LKNTVRYLHEAFEFYEETLSTRYPFSCYKQVFVDELDTDISAYATMSIASVNLLHSIAIIDQTYI 333
            ||:|..|:||.||||||.|:.|||:||:|.||:||...:::|||:|||.|.|||||..|||:|.:
Mouse   281 LKHTTSYIHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPL 345

  Fly   334 SRTFMSRAVAEQFFGCFITSHHWSDTWLAKGIAEYLCGLYSRKCFGNNEYRAWVQSELARVVRYE 398
            :|..:::|:|:|||||||:...|||.|:.|||:.|:.||:.:|.||.|||..|::.||.::|.||
Mouse   346 TRRCLAQALAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYHHWIKEELDKIVAYE 410

  Fly   399 EQYGGIILDCSQPPAPLPVSGTNQSAASSKQQEIVH-YFPIKSLHTVSPKYVEAMRRKAHFVIRM 462
            .:.||::|.        |:.|    ....|.....| :|.||..||:|.:|....:.|||.|:|:
Mouse   411 LKTGGVLLH--------PIFG----GGKEKDNPASHLHFSIKHPHTLSWEYYTMFQCKAHLVMRL 463

  Fly   463 LENRIGQELLIQVFNKQLALASSAATTKIGAGLWSQLLISTNIFIKAIFTVTGKDMSVFMDQWVR 527
            :||||..|.::|||||.|:|||:|::.|..:.:|||:|:||..|:|:|..|:|||:...:.|||.
Mouse   464 IENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTYGFLKSISNVSGKDIQPLIKQWVD 528

  Fly   528 TGGHAKFSLTSVFNRKRNTIELEIRQDYVNQRGIRKYNGPLMVQLQELDGTFKHTLQIESTLVKS 592
            ..|..||..:..||||||.:||||:|||.:. |.:||.|||.|.:|||||:|.||||||...:|.
Mouse   529 QSGVVKFYGSFAFNRKRNVLELEIKQDYTSP-GTQKYVGPLKVTVQELDGSFNHTLQIEENSLKH 592

  Fly   593 DITCHSKSRRNKKKKIPLCTGEEVDMDLSAMD-DSPVLWIRLDPEMILLRDLIIEQPDFQWQYQL 656
            ||.|||||||||||||||..|||||||||||| |||:||||:||:|.:||.:..||.||.|||:|
Mouse   593 DIPCHSKSRRNKKKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYEL 657

  Fly   657 RHERDVTAQFQAIQALQKYPTNATRLALTDTIESERCFYQVRCEAAHSLTKVANQMVASWSGPPA 721
            |:||||.||.::|.||:|:||.|:||||||.:|.|:|||:||..|...|.|:||.||::|:||||
Mouse   658 RYERDVVAQQESILALEKFPTPASRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPA 722

  Fly   722 MLNIFRKFFGSFSAPHIIKLNNFSNFQLYFLQKAIPVAMAGLRTSHGICPPEVMRFLFDLFKYNE 786
            |.::|.:.|...:.|:|:|.|||.:||.|||||.:|||||.||..|.:||.||:.|:.||.|||:
Mouse   723 MKSLFTRMFCCKTCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYND 787

  Fly   787 NSRNHYTDAYYRAALVEALGETLTPVVSVAIHGTQITTDSLSTDAKLVLDEVTRLLNMEKHLPSY 851
            |.:|.::|.||||.:::||..::||.|||  :....|.|:|:.|.:|:|:|:||.|||||.||||
Mouse   788 NRKNKFSDNYYRAEMIDALANSVTPAVSV--NNEVRTLDNLNPDVRLILEEITRFLNMEKLLPSY 850

  Fly   852 KYMVSVSCLKVIRKLQKFGHLPSLPHIYRSYAEYGIYLDLRIAAMECLVDFVKVDGRSEDLEHLI 916
            ::.::||||:.||.|||.||:||...:::||||||.::|:||||:|.:||:.|||...|:|:.|:
Mouse   851 RHTITVSCLRAIRVLQKNGHVPSDASLFKSYAEYGHFVDIRIAALEAVVDYTKVDRSYEELQWLL 915

  Fly   917 TLLETDPDPAARHALAQLLIDNPPFTRESRSRLDKPNLVDRLWFSINR-LPYDTKLRCDIVDLYY 980
            .:::|||.|..||.:..:|..|||||:...|.|....|||:||..:|. ..:|.:|||..||||:
Mouse   916 NMIQTDPVPYVRHKILNMLTKNPPFTKNMESPLCNEALVDQLWKLMNSGTAHDWRLRCGAVDLYF 980

  Fly   981 ALYGTKRPNCLQAGE--------------NQSFYKDLMKDNNSSVGS------VTGSFKKTSDSK 1025
            .|:|..||:||...|              |.:...:....|..|..:      :.|.....|.|:
Mouse   981 TLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPEAGVGNQESASNPGCHAQLAGFQNPFSSSQ 1045

  Fly  1026 SHLPTPTNTLD----------NEPQERQKPAMVTIKRTATEA-----FEVGDEII-------KLE 1068
            .......:|:.          |..:....|.:...:.:.:.:     ..:|.:|.       .:|
Mouse  1046 DEEEVDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPSGSRSSLMPQHSLGCDITPPTKPQWSME 1110

  Fly  1069 RSEEITVLDEPVNVQAYDSETKVNALQADEEARDTHQAAKRLKNEMYAEDDNSSTMLDVGDSTRY 1133
            .|.:....::|:       |..|:::.|             ....|:|::..||.     .|..:
Mouse  1111 LSRKGAGKEQPL-------EMGVHSMVA-------------APLSMFAKEALSSR-----HSEHH 1150

  Fly  1134 ESSHEEGKLKSGDGGLKKKKKKEKKKHKHKHKHRH-SKDKDKD 1175
            ...|.|           .||||:|.||||||||:| |||||::
Mouse  1151 HHHHHE-----------HKKKKKKHKHKHKHKHKHDSKDKDRE 1182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf2	NP_001261668.1	M1_TAF2	16..544	CDD:189018	261/532 (49%)
Taf2	XP_011243959.1	M1_like_TAF2	28..527	CDD:341074	248/503 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849334
Domainoid	1	1.000	572	1.000	Domainoid score	I229
eggNOG	1	0.900	-	-		E1_KOG1932
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31137
Inparanoid	1	1.050	1084	1.000	Inparanoid score	I243
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57568
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004794
OrthoInspector	1	1.000	-	-		oto94396
orthoMCL	1	0.900	-	-		OOG6_102824
Panther	1	1.100	-	-	LDO	PTHR15137
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1471
SonicParanoid	1	1.000	-	-		X4475
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790