Protein Alignment Ciz1 and Ciz1

DIOPT Version :10

• Sequence 1: NP_648367.1
• Gene: Ciz1 / 39161
• FlyBaseID: FBgn0027567
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: XP_006498334.1
• Gene: Ciz1 / 68379
• MGIID: 1920234
• Length: 866
• Species: Mus musculus
• Alignment Length: 698
• Identity: 119/698 - (17%)
• Similarity: 240/698 - (34%)
• Gaps: 172/698 - (24%)

  Fly   131 PSSSSQ-NIGSSSSNYHQRSSTGGGGNNGGSSSSYRP---RDDSTSGSR----------HQRDGS 181
            |.:.|| |....::....|:.:....|...|||...|   |:|.|.||.          ..:|..
Mouse   168 PINPSQLNHSGRNTQKQARTPSSTTPNRKDSSSQTVPLEDREDPTEGSEEATELQMDTCEDQDSL 232

  Fly   182 MG--------------------PPKRMMRSVA-----------------GTNYISRPRGTMSMRG 209
            :|                    ||.:..|.|.                 .::..|..:|......
Mouse   233 VGPDSMLSEPQVPEPEPFETLEPPAKRCRRVRIKGIDHHNWLFAYLWIFASSEESTEKGPTGQPQ 297

  Fly   210 GMMRTGMRVGGMRVVRT--RVNESNDLRTMRRQLLYAQQKDRARLLKIQQLKSSLRRQRQGGNSS 272
            ..::...::...:..:|  |:.|..:::.:.|        .:.:.|:| |.:..|.||.|...|.
Mouse   298 ARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPR--------IQPQALQI-QTQPKLLRQAQTQTSP 353

  Fly   273 DDSSGKEDKDGEDAEKSKKKKGKDKDADGGDESDDDDDDEEDDDEKDEKSKKTSPGKKRNKSANN 337
            :..:.::|:...........:.:.::.|..:::......:.....:.:|..:|....:....|.:
Mouse   354 EHLAPQQDQVEPQVPSQPPWQLQPRETDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPTQAQS 418

  Fly   338 EDKSEAEGNDD----------------------DDDDDDEHGDGDDDDDKDLNESDPKSAKADDA 380
            ::::..:..|.                      :........:...|.||.|.|  |.||:   :
Mouse   419 QEQTSEKTQDQPQTWPQGSVPPPEQASGPACATEPQLSSHAAEAGSDPDKALPE--PVSAQ---S 478

  Fly   381 SDDEDVKVKGDGED-GDGDKSDEK------AKSS-----VEKSGKKKDKDDAKDSKSKKSSSTKK 433
            |:|...:....|.| |:.:|...:      |.||     ::.|..:........|..:...||..
Mouse   479 SEDRSREASAGGLDLGECEKRAGEMLGMWGAGSSLKVTILQSSNSRAFNTTPLTSGPRPGDSTSA 543

  Fly   434 ERTSRKDKDKESSGDDRSKERRSSRHRDEDHNNRKRSFIKLICVHCRIKCVTFKEYNYHLNSRSH 498
            .........|:|                          ::..|..|:....:.:|:..|::...|
Mouse   544 TPAIASTPSKQS--------------------------LQFFCYICKASSSSQQEFQDHMSEAQH 582

  Fly   499 KNSMRQVALNQRADLQRMRARQRTTQREIEENSKEEHESRYCRLCRLAYRQPKNLHQASEHHKTI 563
            :..:.::..:.:..|..:....|..   :|:.:::....|:|..|::.|......|:.::.||..
Mouse   583 QQRLGEIQHSSQTCLLSLLPMPRDI---LEKEAEDPPPKRWCNTCQVYYVGDLIQHRRTQEHKVA 644

  Fly   564 KKFLMPYCGSCHLAFKNAMLYENHRCSLDHIRNKAR-----NDESGSDDSVDEREIDLNKFHTVD 623
            |:.|.|:|..|:..||....:..|..|..| ::||:     ..|:||.|.        :.|.|||
Mouse   645 KQSLRPFCTICNRYFKTPRKFVEHVKSQGH-KDKAQELKTLEKETGSPDE--------DHFITVD 700

  Fly   624 SVGEIDVDMIDADVDAMVTEAEAALKSEDE------------------ET-RKRALIGPDYIKVI 669
            :||..:....:.:.|....|.|..:::|:|                  || ......|.|::..:
Mouse   701 AVGCFESGQEEDEDDDEEEEEEGEIEAEEEFCKQVKPRETSSEQGKGSETYNPNTAYGEDFLVPV 765

  Fly   670 EAFYCELCNHYSAKADDVSLEDYTKKHCMQHSHVKAFLRNKEETEKKN 717
            ..:.|::|:.:.....::.|     .||...:|    ..|.::.:.||
Mouse   766 MGYVCQICHKFYDSNSELRL-----SHCKSLAH----FENLQKYKAKN 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ciz1	NP_648367.1	None
Ciz1	XP_006498334.1	PRK10263	<293..>482	CDD:236669	34/222 (15%)
		GIY-YIG_SF	620..>687	CDD:472790	18/71 (25%)
		C2H2 Zn finger	621..641	CDD:275371	6/24 (25%)
		zf-C2H2_jaz	651..675	CDD:432381	6/23 (26%)
		C2H2 Zn finger	652..674	CDD:275371	6/21 (29%)
		ZnF_U1	767..800	CDD:197732