Protein Alignment Ciz1 and Pep

DIOPT Version :10

• Sequence 1: NP_648367.1
• Gene: Ciz1 / 39161
• FlyBaseID: FBgn0027567
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: XP_061500341.1
• Gene: Pep / 1275094
• VectorBaseID: AGAMI1_002413
• Length: 692
• Species: Anopheles gambiae
• Alignment Length: 950
• Identity: 171/950 - (18%)
• Similarity: 268/950 - (28%)
• Gaps: 420/950 - (44%)

  Fly    48 YHNNNNRYNNHNNSGGGAGGNSHYDNRSRDKFTHHNSSSGRYESSSSSHKRSYDSSRDRSDDRKR 112
            |.|||||......||||.||
Mosquito     3 YRNNNNRRGGGGGSGGGGGG--------------------------------------------- 22

  Fly   113 PRQDDYRRTSSSNDRSDRPSSSSQNIGSSSSNYHQRSSTGGGGNNGGSSSSYRPRDDSTSGSRHQ 177
                                                |..||||..|||||::
Mosquito    23 ------------------------------------SGGGGGGGGGGSSSNF------------- 38

  Fly   178 RDGSMGPPKRMMRSVAGTNYISRPRGTMSMRGGMMRTGMRVGGMRVVRTRVNESNDLRTMRRQLL 242
                            |.||.:|          :......|||:||....::.:|.|
Mosquito    39 ----------------GNNYGNR----------INPWDAGVGGVRVNNDALSFANSL-------- 69

  Fly   243 YAQQKDRARLLKIQQLKSSLRRQRQGGNSSDDSSGKEDKDGEDAEKSKKKKGKDKDADGGDESDD 307
                        |..|..
Mosquito    70 ------------INNLLG----------------------------------------------- 75

  Fly   308 DDDDEEDDDEKDEKSKKTSPGKKRNKSANNEDKSEAEGNDDDDDDDDEHGDGDDDDDKDLNESDP 372
                                    |::||::..|..:|                          .
Mosquito    76 ------------------------NQNANHQVPSLLDG--------------------------V 90

  Fly   373 KSAKADDASDDEDVK---VKGDGEDGDGDKSDEKAKSSVEKSGKKKDKDDAKDSKSKKSSSTKKE 434
            :|::.||.:....::   .|....:|.|.:..:....|.....|..:|...||:.....:|::.:
Mosquito    91 QSSRFDDMNGYNFIRNRYTKNRNINGRGIRKPDAVVRSKNVLSKNYNKPLGKDALGNAGTSSRND 155

  Fly   435 RTSRK--DKDKESSGDDRSKERRSSRHRDEDHNNRKRSFIKLICVHCRIKCVTFKEYNYHLNSRS 497
            .:..|  .|...:.|.....:.:||..:...:.:....|  |.|..|.........:..|:..|:
Mosquito   156 HSGNKGVKKGNPAGGPVGGSKEKSSTSKVSPYMDVSNDF--LYCHMCDKHMYDATSFENHITGRT 218

  Fly   498 H---KNSMRQVALNQRADLQRMRARQRTTQREIE-------ENSKEEHESR-YCRLCRLAYRQPK 551
            |   |.|:.: :...||.|.|..||.....:.||       ..:|..::.| ||.:|.|.:....
Mosquito   219 HRVMKESIEE-SYRMRATLLRQEARIAEQLKTIEIDRLKRMGKAKNYYKVREYCPMCELFFYGHI 282

  Fly   552 NLHQASEHHKTIKKFLMPYCGSCHLAFKNAMLYENHRCSLDHIRN------------KAR----- 599
            ..|:.||.|..:||||.|.|..|.|.|.|...|::|..|:.|::|            ||:
Mosquito   283 IAHRRSEKHLDLKKFLHPKCDDCELEFHNRTEYDDHLLSVVHMKNCKSKPSRLEIERKAKQLTIS 347

  Fly   600 --NDE--------------------------------------------SGSDDSVDEREI---- 614
              |||                                            .|::::.:..::
Mosquito   348 TMNDELLDIREEIAPKKRKEKDTSGTSTKKSDIEGKSATKTQLAEQSASGGTEENGESSKVGEEG 412

  Fly   615 ------------DLNKFHTVDSVG-EIDVDMIDADV--DAMVTEAEAA-----LKSEDE------ 653
                        |.:|....|.|| .:|...:|.:.  |.||.|.|:.     .|..||
Mosquito   413 TAMAEATADDAGDCSKPSVEDGVGATLDDPKLDEECPEDEMVKEEESEDCILDYKPGDEIAPEID 477

  Fly   654 ----ETRKRALIGPDYIKVIEAFYCELCNHY--SAKADDVSLEDYTKKHCMQHSHVKAFLR---- 708
                ..:|...:|...|..:|...|.:|:.|  |....:|        |...|||.:||:|
Mosquito   478 NKLPRYKKNRALGLSLIGKLECVECRICHKYFDSEATGEV--------HARTHSHYRAFIRFLNE 534

  Fly   709 -----------------NKEETEKKNKTEEGDEDDHDDDKKAGDDDADGDEDIDGKLNEDDDEYD 756
                             ..|..:||.|..       |:.|..|:.:.:...:.:|: .:|.|.||
Mosquito   535 KAMEVRIAQKRAVVALEEAEAAKKKQKLV-------DEKKCTGEQNGEQANNGEGE-KKDSDLYD 591

  Fly   757 -----DDGDAEVEEGDATNDKKMWEEVDKDLGDLLAEVETRGHKEDEEDEEDESVLNIDIESEKN 816
                 :.|||.:.|...::|                     ||...|:.|..|:....|:.. |:
Mosquito   592 PSEATESGDASMAEDGKSDD---------------------GHNGSEQVEPMETEAASDLVG-KD 634

  Fly   817 KAKDGKEEANGDTDEGAAKENAPVAKSPEKKHAASAPTTP 856
            .|:.....||.| ||..|:..|..:|..:.|.:......|
Mosquito   635 GARTSTTPANED-DESGAQTEADSSKEDDSKESKDDKPNP 673