Protein Alignment CG8108 and ciz1a

DIOPT Version :9

• Sequence 1: NP_648367.1
• Gene: CG8108 / 39161
• FlyBaseID: FBgn0027567
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: XP_009299400.1
• Gene: ciz1a / 103911032
• ZFINID: ZDB-GENE-100922-222
• Length: 729
• Species: Danio rerio
• Alignment Length: 711
• Identity: 139/711 - (19%)
• Similarity: 266/711 - (37%)
• Gaps: 153/711 - (21%)

  Fly   184 PPKRMMRSVAGTNYISRP----RGTMSMR--GGMMRTGMRVGGMRVVRTRVNESNDLRTMRRQLL 242
            ||.||:...:.|..|..|    :|.:.|:  .|.|| |..:||.:...
Zfish    85 PPARMVNLCSATQTIIAPNPMLQGALLMQQMQGSMR-GFAMGGQQFPP----------------- 131

  Fly   243 YAQQKDRARLLKIQQLKSSLRRQRQGGNSSDDSSGKE-DKDGEDAEKSKKKKGKDKDAD--GGDE 304
            :.....||.||....:..:::....|.........:. ..|.:..:..:|::.:.|.|:  .|..
Zfish   132 FFAAGSRASLLGPVPMGVAIKTPHMGFPRHFTPHARYFPNDYQTPQPDRKREIEQKSANISSGHS 196

  Fly   305 SDDDDDDEEDDDEKDEKSKKTSPGKKRNKSANNEDKSEAEGNDDDDDDDDEHGDGDDDDDKDLNE 369
            :....:.:.:       :.::|.|:...||:::.|:|.|..:          .:|.........:
Zfish   197 AASSSNGQPE-------AARSSNGQSAAKSSSSNDQSAANSS----------SNGQSVASSSNGQ 244

  Fly   370 SDPKSAKADDAS-DDEDVKVKGDGEDGDGDKSDEKA--KSSVEKSGKKKDKDDAKDSKSKKSS-- 429
            |:.||:.:..:| .||.|.|...|..|..::.||.|  |...::|.:..:||.|::::.|..:
Zfish   245 SEAKSSSSSSSSRADEAVAVADPGSQGSSEQPDEPAAKKHKTQESEEPLEKDSAENTECKSPADA 309

  Fly   430 --------------STKKERTSRKDKDKESSGDD-------------------RSKERRSSRHRD 461
                          :|:.|...:.||..:::..|                   :..|....:|:.
Zfish   310 GDSLPEESVVNEPPATEAEEQCQADKQTDAADVDQPISGAPADAGSSDSVSAVKQPEAAPVQHQL 374

  Fly   462 EDHNNRKRSFIKLICVHCRIKCVTFKEYNYHLNSRSHKNSMRQVALNQRADLQRMRARQRTTQRE 526
            .|......|.....|..|.|.|...:.:..|:|..:|:..|.::.....|.|..:..|   .|..
Zfish   375 TDTAAAAESSSSFFCYICNITCHNQQNFQSHMNGLTHQQKMMEIQHMSNACLVTLLPR---VQES 436

  Fly   527 IEENSKEEHE-----SRYCRLCRLAYRQPKNLHQASEHHKTIKKFLMPYCGSCHLAFKNAMLYEN 586
            ::..::::.|     .|:|..|:..:......|:.::.||...:.....|..|.|.|:.|..:..
Zfish   437 LQGAARKDGEKRPGLQRWCSTCQTHFTSNVMEHRRTKEHKRFSRSSSSSCTVCKLNFRTAREFVE 501

  Fly   587 HRCSLDHIRNKARN--DESGSDDSVDEREIDLNKFHTVDSVGEIDVDMIDAD--------VDAMV 641
            |..|.:| :.:.:.  .|||| .||:|       .:||..:||.|.:....|        .:.:.
Zfish   502 HMQSAEH-KQRVQQLWKESGS-GSVEE-------LNTVMLLGEDDGEFCSDDEREDEENGKEGLS 557

  Fly   642 TEAEAALK--SEDEETRKRALIGPDYIKVIEAFYCELCN---HYSAKADDVSLEDYTKKHCMQHS 701
            .:.|..::  .||||.....:.|..::..:..|.|.||:   ||.:.|              :|:
Zfish   558 AQMEVTMEDLDEDEEFDSDTVYGSSFVVPVSGFLCRLCDQFYHYESSA--------------RHA 608

  Fly   702 HVKAFLRNKEETEKKNKTEEGDEDDHDDDKKAGDDDADGDEDI-----DGKLNEDDDEYDDDGDA 761
            |.|. |::.:..::....::     |:|   :|...|:..|::     :|.|..::...|...
Zfish   609 HCKT-LKHFQNLKRYKALKK-----HED---SGSTSAEAAEEVAVAAAEGLLIAEESSVDPSA-- 662

  Fly   762 EVEEGDATNDKKMWEEVDKDLGDLLAEVETRGHKEDEEDEEDESVLNIDIESEKNKAKDGK 822
                ...||......:.::.|     |.|.....|.|.:.|.|..|..:.|.|:..::.|:
Zfish   663 ----SPITNTSSTPPQQEEKL-----EPEETLKPEPEPESELEEKLEPEPELEERSSERGR 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8108	NP_648367.1	None
ciz1a	XP_009299400.1	DUF2413	267..>375	CDD:287302	18/107 (17%)
		ZnF_U1	387..414	CDD:197732	7/26 (27%)
		C2H2 Zn finger	455..475	CDD:275371	3/19 (16%)
		C2H2 Zn finger	486..508	CDD:275371	7/21 (33%)
		ZnF_U1	587..622	CDD:197732	11/49 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575747
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005683
OrthoInspector	1	1.000	-	-		oto40689
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15491
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030