DRSC/TRiP Functional Genomics Resources

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Protein Alignment iPLA2-VIA and nfkbiab

DIOPT Version :9

Sequence 1:NP_729565.2 Gene:iPLA2-VIA / 39160 FlyBaseID:FBgn0036053 Length:887 Species:Drosophila melanogaster
Sequence 2:NP_955923.1 Gene:nfkbiab / 323099 ZFINID:ZDB-GENE-030131-1819 Length:312 Species:Danio rerio


Alignment Length:239 Identity:54/239 - (22%)
Similarity:102/239 - (42%) Gaps:45/239 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   198 SVFHYAASTTKEIINLIIDKSTVNLNHLNSDGYTPLHVACLADKPENVKALLLAGANVNLNAKDI 262
            ::.|.|.....::|.|  .:....||..|:...|.||:|.:.|:|..|:.||.||.:.:|     
Zfish    80 AIIHEATDAALKMIAL--SRRDPFLNIQNNQRQTALHLAIITDQPLIVEQLLKAGCDASL----- 137

  Fly   263 RKVYKTSAPTTVSSFLRTNVSKLYTQDMKYGGTPLHWCSSRETL--HALIMEGCD------VNAT 319
                                    ..|  :|.|.||....:.:|  ..|:.:||.      :...
Zfish   138 ------------------------VDD--HGNTALHIACRKGSLACFGLLTQGCSQHLSAILQTP 176

  Fly   320 NFDGRTALHVMVARNRFECVVTLLAHDAEIDVLDK-DGNAALHIAIEKKLVPIVQCLVVFGCDIN 383
            |::|:..:||:..:.....:.:|:...|:|:..:: :|..|||:|::.:...:|:.|:..|..::
Zfish   177 NYNGQKCIHVVAIQGYLSLLESLIQLGADINAQEQCNGRTALHLAVDLQNFDMVKLLIEKGASVH 241

  Fly   384 LKNKDGKTPRHMVGNDASGNKD-DEILYILHSVGAKRCKDTGSK 426
            .....|.||.|:  .....|.| .::||.|.|...:...::.|:
Zfish   242 SVTYGGHTPYHL--TYGRSNADIQKVLYELTSPHLRELPESDSE 283

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
iPLA2-VIANP_729565.2 ANK repeat 166..226 CDD:293786 6/27 (22%)
Ank_2 168..258 CDD:289560 18/59 (31%)
ANK 191..343 CDD:238125 32/152 (21%)
ANK repeat 228..261 CDD:293786 12/32 (38%)
ANK 291..412 CDD:238125 31/130 (24%)
ANK repeat 292..320 CDD:293786 8/35 (23%)
Ank_2 297..386 CDD:289560 21/97 (22%)
ANK repeat 322..353 CDD:293786 6/30 (20%)
ANK repeat 355..386 CDD:293786 8/30 (27%)
ANK repeat 388..417 CDD:293786 10/29 (34%)
Pat_PNPLA9 563..876 CDD:132851
nfkbiabNP_955923.1 Ank_2 <68..139 CDD:289560 19/89 (21%)
ANK repeat 72..106 CDD:293786 6/27 (22%)
ANK 103..234 CDD:238125 36/161 (22%)
ANK repeat 110..139 CDD:293786 12/57 (21%)
Ank_2 113..241 CDD:289560 35/158 (22%)
ANK repeat 141..210 CDD:293786 15/68 (22%)
Ank_5 167..221 CDD:290568 11/53 (21%)
ANK repeat 213..241 CDD:293786 8/27 (30%)
Ank_2 218..>268 CDD:289560 13/51 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170591957
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.930

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