DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10809 and AgaP_AGAP007703

DIOPT Version :9

Sequence 1:	NP_001163403.1	Gene:	CG10809 / 39159	FlyBaseID:	FBgn0036052	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	XP_001237043.1	Gene:	AgaP_AGAP007703 / 4576287	VectorBaseID:	AGAP007703	Length:	319	Species:	Anopheles gambiae

Alignment Length:	336	Identity:	84/336 - (25%)
Similarity:	143/336 - (42%)	Gaps:	71/336 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 SSPNTHGEWPHMNINLNLNMSSNPSTNASFQLSRDRGEHFALPHLPPLPLNPNASNAEYLPSLIH 129
            |.||.....|...:....:..|:.|.:.:.|.:.:..:.  .|...|.   .:|:::.....|.|
Mosquito    10 SGPNDTSAIPATAVEAEKDSESDSSISCAKQTADNNDDE--CPKTFPF---TDANDSPSAGDLAH 69

  Fly   130 PSTLPSGSKSFKMRPRMQRLKH-SYSY-----SNIIVQSNGRKLRTAASTCNIELLNRILEGGAN 188
                 |...:.|:|.:..||:: |..|     |.::|.    :...|.|..|.|.:..::..|.:
Mosquito    70 -----STRCNLKVRTKCHRLQNRSSPYRTIRPSALLVS----RFLEAVSHNNTEKVQEMIHQGMS 125

  Fly   189 PNAADEY-NRSPLHLAACRGYIPIVQQLLKYGANPNVVDSLGNTPLHLAVISASSNNFNVVVGVL 252
            ||.::.| |||.||:|..||:..||:.||:.|||||:.|...||||||    |||.....||.:|
Mosquito   126 PNTSESYFNRSALHIACSRGFRDIVRLLLENGANPNIRDKNMNTPLHL----ASSTESVEVVQML 186

  Fly   253 LQGGASVHMYDRSNKSPLELAEAKLRL---LRNRYDHPT--------PETAKILEDMCMLTTLIL 306
            |..|.:|.:.|.:....|:.:..||||   |.::....|        .:||    |:|.....:.
Mosquito   187 LDYGTNVLLRDSNGLLALDFSIGKLRLSERLISKMQKLTQSDIHKHREKTA----DVCERIFAVF 247

  Fly   307 RYMVK---------QQRELE------------------DLSALEKRLQNLSTSDDQEQVVSQTAD 344
            :..|:         .|.:||                  ||.::..::.||....:    :....:
Mosquito   248 KQQVRNLDLPRQGLDQEKLEQMLNDFSEQLGKVRQRHIDLDSIVDQISNLKVKSE----IDSDVN 308

  Fly   345 ELLASVERLSI 355
            .||:::::.::
Mosquito   309 SLLSTLQQFTL 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10809	NP_001163403.1	Ank_2	167..263	CDD:289560	41/96 (43%)
		ANK repeat	167..193	CDD:293786	7/25 (28%)
		ANK	170..276	CDD:238125	43/106 (41%)
		ANK repeat	195..226	CDD:293786	18/31 (58%)
		ANK repeat	228..263	CDD:293786	15/34 (44%)
AgaP_AGAP007703	XP_001237043.1	ANK repeat	102..131	CDD:293786	7/32 (22%)
		Ank_2	104..197	CDD:289560	41/96 (43%)
		ANK	107..208	CDD:238125	43/104 (41%)
		ANK repeat	133..164	CDD:293786	17/30 (57%)
		ANK repeat	166..197	CDD:293786	15/34 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BJ6N
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto106434
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770