DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10809 and Git

DIOPT Version :9

Sequence 1:	NP_001163403.1	Gene:	CG10809 / 39159	FlyBaseID:	FBgn0036052	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_610599.3	Gene:	Git / 36122	FlyBaseID:	FBgn0033539	Length:	731	Species:	Drosophila melanogaster

Alignment Length:	344	Identity:	83/344 - (24%)
Similarity:	126/344 - (36%)	Gaps:	111/344 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 ASKGIMITPP--PPAMPPTPTSSPNTHGEWPHMNINLNLNM-----SSNPSTNASF--------- 94
            |.:.:.|.||  ..:.|.|||.|  |..:.|.....|...:     :.:||. ||.
  Fly    10 AHRKLFIAPPDLDHSDPATPTIS--TRSKMPRGKSRLQTEVCGDCGAGDPSW-ASINRGILLCAD 71

  Fly    95 --QLSRDRGEHFAL----------PHLPPL--PLNPNASNAEYLPSLIHPSTLPSGSK------- 138
              .:.|..|.|.::          |.:...  .||.:.:|:.:...|:..||..:|.|
  Fly    72 CCSVHRSLGRHISIVKSLRQGNWEPSVLNFVNSLNAHGANSVWEHHLLDGSTNSTGGKHVPRWRK 136

  Fly   139 ----------------------SFKMRPRMQRLKHSYSYSNIIVQSNGRKLRTAASTCNIELLNR 181
                                  :|.::|.:|........:..:.|...|:|..:..|.|:|...|
  Fly   137 PTPKDALHPTKSDFIKAKHVNLTFVLKPSLQDDDDGNGSAGCLEQELSRQLHASVRTSNLETSLR 201

  Fly   182 ILEGGANPNAADEYNRS-PLHLAACRGYIPIVQQLLKYGANPNVVDSLGNTPLHLAVISASSNNF 245
            .|..||:||...|...| |||:||..|....::.||.|||:.|.:|..|.|||.|    |.:||.
  Fly   202 FLVQGADPNYYHEDKLSTPLHMAAKFGQASQIEMLLIYGADVNALDGNGMTPLEL----ARANNH 262

  Fly   246 NVVVGVLLQGGASVHMYDRSN--------KSP---------------------LELAEAKLRLLR 281
            |.:...||..     |||.::        |.|                     |::|..||:|:.
  Fly   263 NTIAERLLDA-----MYDVTDRIITFLGGKKPDHASGRHMIIPDANGADISEQLKIARGKLQLVP 322

  Fly   282 NRYDHPTPETAKILEDMCM 300
            |          |:.|::.|
  Fly   323 N----------KMFEELVM 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10809	NP_001163403.1	Ank_2	167..263	CDD:289560	37/96 (39%)
		ANK repeat	167..193	CDD:293786	10/25 (40%)
		ANK	170..276	CDD:238125	42/135 (31%)
		ANK repeat	195..226	CDD:293786	13/31 (42%)
		ANK repeat	228..263	CDD:293786	12/34 (35%)
Git	NP_610599.3	ArfGap	48..164	CDD:279720	17/116 (15%)
		Ank_2	187..279	CDD:289560	39/100 (39%)
		ANK	<187..270	CDD:238125	34/86 (40%)
		ANK repeat	187..213	CDD:293786	10/25 (40%)
		ANK repeat	215..247	CDD:293786	13/31 (42%)
		ANK repeat	249..279	CDD:293786	14/38 (37%)
		GIT_SHD	314..342	CDD:285690	8/28 (29%)
		GIT	374..404	CDD:128828
		GIT1_C	609..727	CDD:289013
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910