DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10809 and Ankrd46

DIOPT Version :9

Sequence 1:	NP_001163403.1	Gene:	CG10809 / 39159	FlyBaseID:	FBgn0036052	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001013970.1	Gene:	Ankrd46 / 299982	RGDID:	1309382	Length:	228	Species:	Rattus norvegicus

Alignment Length:	192	Identity:	56/192 - (29%)
Similarity:	78/192 - (40%)	Gaps:	39/192 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 SYSYSNIIVQSNGRKLRTAASTCNIELLNRILEGGANPNAADEYNRSPLHLAACRGYIPIVQQLL 216
            ||.:.|...|:|...|: |....:.....|:||.|.:||..|...|:.|||||.||.:.|.|.|.
  Rat     2 SYVFVNDSSQTNVPLLQ-ACIDGDFTYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLH 65

  Fly   217 KYGANPNVVDSLGNTPLHLAVISASSNNFNVVVGVLLQGGASVHMYDRSNKSPLELAEAK----- 276
            |:||:|...|..|||.|||.       .....:..|:..|..:.:.:....:||.||:.:
  Rat    66 KFGADPLATDYQGNTALHLC-------GHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKD 123

  Fly   277 -LRLLR----------NRYDHPTPETAKILEDMCMLTTLILRYMVKQQRELEDLSALEKRLQ 327
             :|||.          ||..|...||.:..|               .:..:|..|.|...||
  Rat   124 VIRLLESLEEQEVKGFNRGTHSKLETMQTAE---------------SESAMESHSLLNPNLQ 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10809	NP_001163403.1	Ank_2	167..263	CDD:289560	33/95 (35%)
		ANK repeat	167..193	CDD:293786	8/25 (32%)
		ANK	170..276	CDD:238125	36/105 (34%)
		ANK repeat	195..226	CDD:293786	15/30 (50%)
		ANK repeat	228..263	CDD:293786	8/34 (24%)
Ankrd46	NP_001013970.1	ANK 1	11..40		9/29 (31%)
		ANK repeat	15..42	CDD:293786	8/27 (30%)
		Ank_2	16..103	CDD:403870	33/94 (35%)
		ANK repeat	44..75	CDD:293786	15/30 (50%)
		ANK 2	44..74		15/29 (52%)
		ANK repeat	77..105	CDD:293786	8/34 (24%)
		ANK 3	77..103		8/32 (25%)
		Ank_2	82..>142	CDD:423045	13/66 (20%)
		ANK 4	107..138		7/30 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870