DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10809 and Ankrd28

DIOPT Version :9

Sequence 1:	NP_001163403.1	Gene:	CG10809 / 39159	FlyBaseID:	FBgn0036052	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	XP_006518432.1	Gene:	Ankrd28 / 105522	MGIID:	2145661	Length:	1083	Species:	Mus musculus

Alignment Length:	168	Identity:	52/168 - (30%)
Similarity:	80/168 - (47%)	Gaps:	13/168 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 LPPLPLNPNASNAEYLPSLIHPSTLPSGSKSFKMRPRMQRLKHSYSYS-NIIVQSNGRKLRTAAS 172
            |.||..|.|.|:.....:|.|        .:|.....|.:|..|...: |...:.:.|.:..||.
Mouse   156 LVPLLSNVNVSDRAGRTALHH--------AAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAY 212

  Fly   173 TCNIELLNRILEGGANPNAADEYNRSPLHLAACRGYIPIVQQLLKYGANPNVVDSLGNTPLHLAV 237
            ..:||::..::..||.....|:.:.:|||.||..|.|.:|:.||..|.:.|..::.||||||:|.
Mouse   213 MGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVAC 277

  Fly   238 ISASSNNFNVVVGVLLQGGASVHMYDRSNKSPLELAEA 275
            .    |..:|||..|:..||:|:..:....:||..|.|
Mouse   278 Y----NGQDVVVNELIDCGANVNQKNEKGFTPLHFAAA 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10809	NP_001163403.1	Ank_2	167..263	CDD:289560	34/95 (36%)
		ANK repeat	167..193	CDD:293786	6/25 (24%)
		ANK	170..276	CDD:238125	38/106 (36%)
		ANK repeat	195..226	CDD:293786	12/30 (40%)
		ANK repeat	228..263	CDD:293786	15/34 (44%)
Ankrd28	XP_006518432.1	ANK repeat	42..68	CDD:293786
		Ank_2	53..>331	CDD:393464	52/168 (31%)
		ANK repeat	70..101	CDD:293786
		ANK repeat	106..134	CDD:293786
		ANK repeat	136..167	CDD:293786	5/10 (50%)
		ANK repeat	170..200	CDD:293786	7/37 (19%)
		ANK repeat	202..233	CDD:293786	7/30 (23%)
		PHA03095	216..>484	CDD:222980	36/100 (36%)
		ANK repeat	235..266	CDD:293786	12/30 (40%)
		ANK repeat	268..299	CDD:293786	15/34 (44%)
		ANK repeat	301..332	CDD:293786	4/11 (36%)
		ANK repeat	335..366	CDD:293786
		ANK repeat	368..393	CDD:293786
		ANK repeat	401..432	CDD:293786
		ANK repeat	434..465	CDD:293786
		ANK repeat	467..498	CDD:293786
		ANK repeat	500..532	CDD:293786
		Ank_2	505..610	CDD:372319
		ANK repeat	582..610	CDD:293786
		PHA02874	584..>893	CDD:165205
		ANK repeat	612..643	CDD:293786
		ANK repeat	648..680	CDD:293786
		ANK repeat	682..713	CDD:293786
		ANK repeat	715..746	CDD:293786
		ANK repeat	748..777	CDD:293786
		ANK repeat	819..850	CDD:293786
		ANK repeat	853..883	CDD:293786
		Ank_2	857..950	CDD:372319
		ANK repeat	885..917	CDD:293786
		ANK repeat	919..950	CDD:293786
		ANK repeat	955..986	CDD:293786
		Ank	957..987	CDD:365815
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910