DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RasGAP1 and AT2G21040

DIOPT Version :9

Sequence 1:	NP_001261664.1	Gene:	RasGAP1 / 39158	FlyBaseID:	FBgn0004390	Length:	1181	Species:	Drosophila melanogaster
Sequence 2:	NP_565496.1	Gene:	AT2G21040 / 816638	AraportID:	AT2G21040	Length:	261	Species:	Arabidopsis thaliana

Alignment Length:	257	Identity:	50/257 - (19%)
Similarity:	88/257 - (34%)	Gaps:	84/257 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 GRFVGVTIKVPACVDLAKKQGTCDPFVVCTAHYSNKHQVTRRTKQRKKTVDPEFDEAMYF----- 335
            |.||   :.|.:..|:..|..| :|:|    |...|.: .|:||..||..||:::|...|
plant    16 GMFV---VIVHSAEDVEGKHHT-NPYV----HIYFKGE-ERKTKHVKKNKDPKWNEEFSFMLEEP 71

  Fly   336 ----DLHIDADAGSTNTTGSNKSAGSLE--------------------SSANKGY-------SIY 369
                .:|:...:.|:......:.| |:|                    |:.:||:       .:.
plant    72 PIHEKMHVKVFSTSSRIVFVLRCA-SVEAAYVPFEGIKPRGAKLFSDGSACSKGFGDTTSFGDMA 135

  Fly   370 PVGGADLVEIVVSVWHDAHGAMSDKVFLGE--------------------------VRLPMLNK- 407
            .:||     :.:.:.|...|.::..|.:.|                          ||...:.:
plant   136 LLGG-----MAIMLAHHDEGVLTCHVMVRESFEEINMAWRAWKLVRQGAGSSGSWFVRRRFVREL 195

  Fly   408 QEQQAVNPSAW-----YYLQPRSMTHSSRSLNATP-RSCATPPGTRLSVDSTIGSLRLNLNY 463
            ..|:||...|.     :..:|......|..:...| :|...|...|..:.||..|.:.:.:|
plant   196 VRQEAVRQGAGLSGSRFVKEPVRQGAGSSGVGVWPLKSQGRPSDLRFFLKSTFSSFKFHDHY 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RasGAP1	NP_001261664.1	C2A_RasA2_RasA3	44..169	CDD:176046
		C2B_RasA3	280..462	CDD:175977	46/250 (18%)
		RasGAP	449..797	CDD:214617	4/15 (27%)
		RasGAP_GAP1_like	473..740	CDD:213330
		PH	761..859	CDD:278594
		PH_GAP1-like	763..867	CDD:269950
		BTK	862..897	CDD:128417
AT2G21040	NP_565496.1	C2	18..>82	CDD:175973	20/72 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010