Protein Alignment Cdk8 and SSN3

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_015283.1
• Gene: SSN3 / 856065
• SGDID: S000005963
• Length: 555
• Species: Saccharomyces cerevisiae
• Alignment Length: 335
• Identity: 152/335 - (45%)
• Similarity: 205/335 - (61%)
• Gaps: 36/335 - (10%)

  Fly    39 KWKETSDGKEYALKQIDGTGLSMSACREIALLRELKHQNVITLIRVFLSHNDRK-VFLLIDYAEH 102
            |:|...||.|    |:..||:|.|||||:||.|||.::::.||:.:||   :|| |.::.:||||
Yeast   184 KFKTEKDGVE----QLHYTGISQSACREMALCRELHNKHLTTLVEIFL---ERKCVHMVYEYAEH 241

  Fly   103 DLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERG 167
            ||..||.||   ...:|:::.|| ||:|:::|:|||:.|||.|||||||||||||:|..|    |
Yeast   242 DLLQIIHFH---SHPEKRMIPPR-MVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTID----G 298

  Fly   168 RVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEP 232
            .|||.|:|.||.|:..|:.|...|.||||.|||||||||||||||.|:|:|::|||||||:..:|
Yeast   299 CVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQP 363

  Fly   233 IFHCRQE--DIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAK 295
            ||...:.  |.|.:.|:..:||.||..|:|.|..|.|..::|.||:..:||           ..|
Yeast   364 IFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITK-----------FPK 417

  Fly   296 YMER-----HKI-KPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQP-TQDVFAGCPIPY 353
            |.:.     |.. ..|..|..||..||..||.|||.:..|::.:||.|...| :::||.|....|
Yeast   418 YRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENVFEGLTYKY 482

  Fly   354 PKREFLTDDD 363
            |.|...|:|:
Yeast   483 PARRIHTNDN 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	140/304 (46%)
SSN3	NP_015283.1	STKc_CDK8_like	74..463	CDD:270834	140/304 (46%)