Protein Alignment Cdk8 and CDKE;1

DIOPT Version :9

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_201166.1
• Gene: CDKE;1 / 836481
• AraportID: AT5G63610
• Length: 470
• Species: Arabidopsis thaliana
• Alignment Length: 456
• Identity: 179/456 - (39%)
• Similarity: 252/456 - (55%)
• Gaps: 78/456 - (17%)

  Fly    20 FNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVIT 80
            :|..| |:|.||||.|:.|:.| |...:..|:|:.    ||.|:|.:|.|||.||||:.|:||:.
plant    25 YNLVG-KIGEGTYGLVFLARTK-TPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVK 87

  Fly    81 LIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSN 145
            |:.|.::..|..::|..||||:||:.||:.||...........    |||||:|:|:|::|||||
plant    88 LVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYT----VKSLLWQLLNGLNYLHSN 148

  Fly   146 WVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARH 210
            |::||||||:|||||||..|.|.|||||.|.||::.||||||:| :.||||.||||||||||::|
plant   149 WIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQAPLKPLSD-NGVVVTIWYRAPELLLGSKH 212

  Fly   211 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTS-NPYHHDQLDRIFNVMGFPQDKDWEDIKKMP 274
            ||.|:|:||:|||||||||.:|:|  :..:.|:| ||:..||||:||.::|.|....|..:..:|
plant   213 YTSAVDMWAVGCIFAELLTLKPLF--QGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLP 275

  Fly   275 EHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEP 339
            ......:..:...|.:..|...:..::..|   |:.||.|:|..||.||||:.||::.:||:.:|
plant   276 HWQNDVQHIQAHKYDSVGLHNVVHLNQKSP---AYDLLSKMLEYDPLKRITASQALEHEYFRMDP 337

  Fly   340 QPTQDVF-AGCP----IPYPKREFLTDDDQEDKSD------------------------------ 369
            .|.::.| |..|    :.||.|...|:.|.|..:.
plant   338 LPGRNAFVASQPMEKNVNYPTRPVDTNTDFEGTTSINPPQAVAAGNVAGNMAGAHGMGSRSMPRP 402

  Fly   370 ---NKRQQQQQQQ-------------------QQQQQQQQQQQQQQQQQQQQQMN----AEPNAK 408
               :..|:.||.|                   |||:...|..||||.:::...|.    |.||..
plant   403 MVAHNMQRMQQSQGMMAYNFPAQAGLNPSVPLQQQRGMAQPHQQQQLRRKDPGMGMSGYAPPNKS 467

  Fly   409 R 409
            |
plant   468 R 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	149/319 (47%)
		S_TKc	22..335	CDD:214567	148/317 (47%)
CDKE;1	NP_201166.1	STKc_CDK8_like	24..333	CDD:270834	149/319 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	284	1.000	Domainoid score	I385
eggNOG	1	0.900	-	-		E1_KOG0666
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I802
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D642369at2759
OrthoFinder	1	1.000	-	-		FOG0002084
OrthoInspector	1	1.000	-	-		oto4081
orthoMCL	1	0.900	-	-		OOG6_102974
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1379
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830