Protein Alignment Cdk8 and cdk1

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_997729.1
• Gene: cdk1 / 80973
• ZFINID: ZDB-GENE-010320-1
• Length: 302
• Species: Danio rerio
• Alignment Length: 334
• Identity: 127/334 - (38%)
• Similarity: 188/334 - (56%)
• Gaps: 57/334 - (17%)

  Fly    16 VEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQ 76
            ::|....|  |:|.||||.|||.:.|.|  |:..|:|:|    :..|:..:|.|||:||:||:|.
Zfish     1 MDDYLKIE--KIGEGTYGVVYKGRNKTT--GQVVAMKKIRLESEEEGVPSTAVREISLLKELQHP 61

  Fly    77 NVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQV-VVPRG------MVKSLLYQ 134
            ||:.|:.|.:  .:.|::|:.::...||             ||.: .:|.|      :|||.|||
Zfish    62 NVVRLLDVLM--QESKLYLVFEFLSMDL-------------KKYLDSIPSGEFMDPMLVKSYLYQ 111

  Fly   135 ILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWY 199
            ||:||.:.|...||||||||.|:|:    :.:|.:|:||.|.||.|..|::....   .|||.||
Zfish   112 ILEGILFCHCRRVLHRDLKPQNLLI----DNKGVIKLADFGLARAFGVPVRVYTH---EVVTLWY 169

  Fly   200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQD 264
            ||||:||||..|:..:|:|:||.|||||.|.:|:||...|         .|||.|||..:|.|.:
Zfish   170 RAPEVLLGASRYSTPVDLWSIGTIFAELATKKPLFHGDSE---------IDQLFRIFRTLGTPNN 225

  Fly   265 KDWEDIKKMPEH-HTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQ 328
            :.|.|::.:|:: :|..|      :.:.:||..::    ..|.....||.|:|:.||.|||::.|
Zfish   226 EVWPDVESLPDYKNTFPK------WKSGNLANTVK----NLDKNGIDLLMKMLIYDPPKRISARQ 280

  Fly   329 AMQDQYFQE 337
            ||...||.:
Zfish   281 AMTHPYFDD 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	124/327 (38%)
cdk1	NP_997729.1	STKc_CDK1_euk	3..287	CDD:270845	125/328 (38%)