Protein Alignment Cdk8 and cdk10

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001017622.2
• Gene: cdk10 / 550285
• ZFINID: ZDB-GENE-050417-94
• Length: 360
• Species: Danio rerio
• Alignment Length: 368
• Identity: 120/368 - (32%)
• Similarity: 190/368 - (51%)
• Gaps: 61/368 - (16%)

  Fly    26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVITLIRVFL 86
            ::|.||||.||:|  ::|...:..|||::    :..|:.:|:.|||.||..|:|.|::.|..|.:
Zfish    45 RIGEGTYGIVYRA--RDTRTNEIVALKKVRMDKEKDGIPISSLREINLLIRLRHPNIVELKEVVV 107

  Fly    87 SHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRD 151
            ..:...:||::.|.|.||        |:.....|.......||.::.|:|.|:.|||.|::||||
Zfish   108 GSHLESLFLVMSYCEQDL--------ASLLENMQSPFSEAQVKCIVLQLLKGLAYLHHNFILHRD 164

  Fly   152 LKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAID 216
            ||.:|:|:    .::|.|||||.|.||::..||:|:.   |.|||.||||||||||.:..|.|:|
Zfish   165 LKVSNLLM----TDKGCVKIADFGLARVYGIPLQPMT---PRVVTLWYRAPELLLGTKTQTTALD 222

  Fly   217 IWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTK 281
            :||:||||||||..:|:.....|         ..|||.|..::|.|.:..|....::|    |..
Zfish   223 MWAVGCIFAELLAHKPLLPGASE---------IQQLDLIVQLLGTPNESIWPGFSRLP----LVG 274

  Fly   282 DF--KRSTYSTCSLAKYMERHKIKPDSKA-FHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPTQ 343
            .:  ::..|:..       ::|....|:| ..||..|.:.:|.:|.|:...::..||:|:|.|.:
Zfish   275 QYSLRKQPYNNL-------KNKFTWLSEAGLRLLNLLFMYNPQRRATAIDCLESSYFKEKPLPCE 332

  Fly   344 DVFAGCPIP-YPKREFLTDDDQEDKSDNKRQQQQQQQQQQQQQ 385
            ...    :| :|...            |||...:.:.|.::.:
Zfish   333 PEL----MPTFPHHR------------NKRSASETEHQTKRSK 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	109/315 (35%)
cdk10	NP_001017622.2	STKc_CDK10	32..340	CDD:173742	115/335 (34%)