Protein Alignment Cdk8 and Cdk8

DIOPT Version :10

• Sequence 1: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001102531.1
• Gene: Cdk8 / 498140
• RGDID: 1560888
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 412
• Identity: 325/412 - (78%)
• Similarity: 352/412 - (85%)
• Gaps: 6/412 - (1%)

  Fly     1 MDYDFKMKTQIERTKVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQIDGTGLSMSACR 65
            ||||||:|...||.:|||||.||||||||||||||||||.|:..|.|:||||||:|||:||||||
  Rat     1 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACR 65

  Fly    66 EIALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKS 130
            ||||||||||.|||:|.:|||||.||||:||.||||||||||||||||:||.||.|.:|||||||
  Rat    66 EIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKS 130

  Fly   131 LLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVV 195
            |||||||||||||:|||||||||||||||||:|.|||||||||||||||||:|||||||||||||
  Rat   131 LLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVV 195

  Fly   196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMG 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMG 260

  Fly   261 FPQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRIT 325
            ||.|||||||||||||.||.|||:|:||:.|||.||||:||:||||||||||||||.|||.||||
  Rat   261 FPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRIT 325

  Fly   326 SEQAMQDQYFQEEPQPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQQQQQQQQQQQQQQ 390
            |||||||.||.|:|.||.||||||.||||||||||:::.::|.|.|.|||||.............
  Rat   326 SEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDEKGDKKNQQQQQGNNHTNGTGHPGN 390

  Fly   391 QQQQQQQQQQMNAEPNAKRVRL 412
            |.....|      .|..|:||:
  Rat   391 QDSGHAQ------GPPLKKVRV 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	277/315 (88%)
Cdk8	NP_001102531.1	STKc_CDK8	3..335	CDD:270851	287/331 (87%)